Bioorganic and Medicinal Chemistry Letters p. 2931 - 2934 (2004)
Update date:2022-08-28
Topics:
Romeo, Sergio
Dell'Agli, Mario
Parapini, Silvia
Rizzi, Luca
Galli, Germana
Mondani, Monica
Sparatore, Anna
Taramelli, Donatella
Bosisio, Enrica
Statine-based inhibitors of Plasmepsin II (PLMII) coupled with Primaquine have been designed using the 'double-drug' approach. The IC50 values for PLMII inhibition ranged from 0.59 to 400nM and the best IC50 value for inhibition of P
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