Synlett p. 765 - 766 (1997)
Update date:2022-08-28
Topics:
Laux, Michael
Krause, Norbert
The ruthenium-catalyzed flash oxidation of β-allenic esters 1 furnishes α,α′-dihydroxyketones 2 in 24-72% yield. In the case of the chiral allene 1e, the oxidation proceeds with good diastereoselectivity (88% de), i.e. with efficient axis to center chirality transfer. The flash oxidation can also be used for the synthesis of corticosteroids, as exemplified by the transformation of allenic steroid 4 into dihydroxyketone 5.
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(1996)