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Gambogic acid

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Name

Gambogic acid

EINECS N/A
CAS No. 2752-65-0 Density 1.296 g/cm3
PSA 119.36000 LogP 7.23930
Solubility N/A Melting Point 88.5°C
Formula C38H44O8 Boiling Point 808.946 °C at 760 mmHg
Molecular Weight 628.763 Flash Point 251.446 °C
Transport Information N/A Appearance N/A
Safety 26-45 Risk Codes 25-36/37/38
Molecular Structure Molecular Structure of 2752-65-0 (GAMBOGIC ACID) Hazard Symbols T
Synonyms

b-Guttiferin;2-Butenoic acid,2-methyl-4-[(1R,3aS,5S,11R,14aS)-3a,4,5,7-tetrahydro-8-hydroxy-3,3,11-trimethyl-13-(3-methyl-2-butenyl)-11-(4-methyl-3-pentenyl)-7,15-dioxo-1,5-methano-1H,3H,11H-furo[3,4-g]pyrano[3,2-b]xanthen-1-yl]-,(2Z)- (9CI);2-Butenoic acid,2-methyl-4-[3a,4,5,7-tetrahydro-8-hydroxy-3,3,11-trimethyl-13-(3-methyl-2-butenyl)-11-(4-methyl-3-pentenyl)-7,15-dioxo-1,5-methano-1H,3H,11H-furo[3,4-g]pyrano[3,2-b]xanthen-1-yl]-,[1R-[1a,1(Z),3ab,5a,11b,14aS*]]-;Gambogic acid (7CI);R-Gambogic acid;1,5-Methano-1H,3H,11H-furo[3,4-g]pyrano[3,2-b]xanthene-1-crotonicacid, 3a,4,5,7-tetrahydro-8-hydroxy-a,3,3,11-tetramethyl-13-(3-methyl-2-butenyl)-11-(4-methyl-3-pentenyl)-7,15-dioxo-,(Z)- (8CI);

 

Gambogic acid Chemical Properties

Chemistry informtion about Cambogic Acid (CAS NO.2752-65-0) is:
Synonyms: Beta-Guttiferin ; Beta-Guttilactone ; Gambogic Acid ; Guttatic Acid ; Guttic Acid ; (Z)-Methyl-3-Pentenyl)- ; 1,5-Methano-1h,3h,11h-Furo(3,4-G)Pyrano(3,2-B)Xanthene-1-Crotonicacid,3a,4,5, ; 3,3,11-Tetramethyl-13-(3-Methyl-2-Butenyl)-11-(4-7-Tetrahydro-8-Hydroxy-Alph
MF: C38H44O8
MW: 628.75 
Density: 1.29 g/cm3
Flash Point: 251.4 °C
Boiling Point: 808.9 °C at 760 mmHg
Vapour Pressure: 1.21E-27 mmHg at 25°C 
Enthalpy of Vaporization: 123.31 kJ/mol
Following is the molecular structure of Cambogic Acid (CAS NO.2752-65-0) is:

Gambogic acid Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mammal (species unspecified) LD50 unreported 55mg/kg (55mg/kg)   "Zhongliu Yanjiu" Cancer Review, Yu, R., et al., eds., Shanghai Science/Technology Publisher,Peop. Rep. China, 1994Vol. -, Pg. 220, 1994.
mouse LD50 subcutaneous 354mg/kg (354mg/kg)   "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 8(1), Pg. 331, 1982.
rat LD50 intraperitoneal 88mg/kg (88mg/kg)
liver: other changes
Indian Journal of Experimental Biology. Vol. 5, Pg. 96, 1967.
rat LD50 intravenous 107mg/kg (107mg/kg)
liver: other changes
Indian Journal of Experimental Biology. Vol. 5, Pg. 96, 1967.

Gambogic acid Safety Profile

Poison by subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits acrid smoke and fumes.

Gambogic acid Specification

 Cambogic Acid (CAS NO.2752-65-0) is golden yellow and brittle material.It is naturally in plants Garcinia hanburyi Hook. F. of dry resin.

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