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Iodamide meglumine
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Name

Iodamide meglumine

 EINECS 242-480-6
CAS No. 18656-21-8 Density g/cm3
PSA N/A LogP N/A
Solubility N/A Melting Point N/A
Formula C12H11I3N2O4•C7H17NO5 Boiling Point 683.4°Cat760mmHg
Molecular Weight 823.20 Flash Point 367.1°C
Transport Information N/A Appearance N/A
Safety Mildly toxic. When heated to decomposition it emits toxic fumes of I− and NOx. Risk Codes N/A
Molecular Structure Molecular Structure of 18656-21-8 (1-deoxy-1-(methylamino)-D-glucitol α,5-diacetamido-2,4,6-triiodo-m-toluate) Hazard Symbols N/A
Synonyms

Iodamide 300;Conraxin H;3-acetamido-5-(acetamidomethyl)-2,4,6-triiodo-benzoic acid; (2R,3R,4R,5S)-6-methylaminohexane-1,2,3,4,5-pentol;D-Glucitol,1-deoxy-1-(methylamino)-,3- (acetylamino)-5-[(acetylamino)methyl]-2,4,6- triiodobenzoate (salt);Iodamide meglumine (USAN);IODAMIDE 380;MEGLUMINE IODAMIDE;IODAMIDE METHYLGLUCAMINE;

 

Iodamide meglumine Chemical Properties

IUPAC Name: 3-Acetamido-5-(acetamidomethyl)-2,4,6-triiodobenzoic acid; (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol
Synonyms of Iodamide meglumine (CAS NO.18656-21-8) :1-Deoxy-1-(methylamino)-D-glucitol a,5-Diacetamido-2,4,6-triiodo-m-toluate (Salt) ; 3-(Acetylamino)-5-((acetylamino)methyl)-2,4,6-triiodobenzoic Acid Compound with 1-Deoxy-1-(methylamino)-D-glucitol (1:1) ; Jodomiron ; Meglumine iodamide ; Uromiro
InChI:InChI=1/C12H11I3N2O4.C7H17NO5/c1-4(18)16-3-6-8(13)7(12(20)21)10(15)11(9(6)14)17-5(2)19;1-8-2-4(10)6(12)7(13)5(11)3-9/h3H2,1-2H3,(H,16,18)(H,17,19)(H,20,21);4-13H,2-3H2,1H3/t;4-,5+,6+,7+/m.0/s1
CAS NO:18656-21-8
Molecular Formula:C19H28I3N3O9
Molecular Weight :823.1537
Molecular Structure :
EINECS: 242-480-6
Flash Point: 367.1 °C
Enthalpy of Vaporization: 105.29 kJ/mol
Boiling Point: 683.4 °C at 760 mmHg
Vapour Pressure: 1.3E-19 mmHg at 25°C

Iodamide meglumine Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD intravenous > 15mL/kg (15mL/kg)   Arzneimittel-Forschung. Drug Research. Vol. 15, Pg. 222, 1965.
guinea pig LD50 intraperitoneal 15gm/kg (15000mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

CARDIAC: OTHER CHANGES		 Arzneimittel-Forschung. Drug Research. Vol. 15, Pg. 222, 1965.
mammal (species unspecified) LD50 oral > 20gm/kg (20000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 15, Pg. 222, 1965.
mouse LD50 intracrebral 200mg/kg (200mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 15, Pg. 222, 1965.
mouse LD50 intravenous 9gm/kg (9000mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

CARDIAC: OTHER CHANGES		 Arzneimittel-Forschung. Drug Research. Vol. 15, Pg. 222, 1965.
rabbit LD50 intravenous 13200mg/kg (13200mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

CARDIAC: OTHER CHANGES		 Arzneimittel-Forschung. Drug Research. Vol. 15, Pg. 222, 1965.
rat LD50 intraperitoneal 17900mg/kg (17900mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

CARDIAC: OTHER CHANGES		 Arzneimittel-Forschung. Drug Research. Vol. 15, Pg. 222, 1965.
rat LD50 intravenous 11400mg/kg (11400mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

CARDIAC: OTHER CHANGES		 Arzneimittel-Forschung. Drug Research. Vol. 15, Pg. 222, 1965.

 

Iodamide meglumine Safety Profile

 Iodamide meglumine (CAS NO.18656-21-8) is mildly toxic. When Iodamide meglumine (CAS NO.18656-21-8) is heated to decomposition, it emits toxic fumes of I− and NOx.

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