The IUPAC name of Benzoic acid,2-amino-5-chloro-, methyl ester is methyl 2-amino-5-chlorobenzoate. With the CAS registry number 5202-89-1, it is also named as 2-Amino-5-chlorobenzoic acidmethyl ester. The product's categories are Fine Chemical & Intermediates; Aromatic Esters; Pharmacetical; Benzoic acid; Acids & Esters; Anilines, Amides & Amines; Chlorine Compounds; C8 to C9; Carbonyl Compounds; Esters. Besides, it is light yellow crystalline, which should be sealed in dark, cool and dry place. In addition, its molecular formula is C₈H₈ClNO₂ and molecular weight is 185.61.

The other characteristics of this product can be summarized as: (1)EINECS: 225-992-4; (2)ACD/LogP: 2.92; (3)# of Rule of 5 Violations: 0; (4)ACD/LogD (pH 5.5): 2.92; (5)ACD/LogD (pH 7.4): 2.92; (6)ACD/BCF (pH 5.5): 97.19; (7)ACD/BCF (pH 7.4): 97.2; (8)ACD/KOC (pH 5.5): 921.17; (9)ACD/KOC (pH 7.4): 921.28; (10)H bond acceptors: 3; (11)H bond donors: 2; (12)Freely Rotating Bonds: 3; (13)Index of Refraction: 1.58; (14)Molar Refractivity: 47.15 cm³; (15)Molar Volume: 141.5 cm³; (16)Surface Tension: 48.6 dyne/cm; (17)Density: 1.311 g/cm³; (18)Flash Point: 131.5 °C; (19)Melting point: 66-68 °C; (20)Enthalpy of Vaporization: 53.35 kJ/mol; (21)Boiling Point: 293.9 °C at 760 mmHg; (22)Vapour Pressure: 0.00168 mmHg at 25 °C.

Preparation of Benzoic acid,2-amino-5-chloro-, methyl ester: this chemical can be prepared by 2-Amino-benzoic acid methyl ester.



This reaction needs AcOH, CH₂Cl₂ and H₂O. The reaction time is 30 min. The yield is 61 %.

Uses of Benzoic acid,2-amino-5-chloro-, methyl ester: this chemical is used as pesticides and pharmaceutical intermediates. Additionally, it can react with 2,5-Dimethoxy-tetrahydro-furan to get 1-(4-Cloro-2-metossicarbonilfenil)pirrolo.



This reaction needs Acetic acid by heating for 30 min. The yield is 65 %.

When you are using this chemical, please be cautious about it as the following: it is irritating to eyes, respiratory system and skin. You should wear suitable gloves and eye/face protection when use it. Moreover, in case of contact with eyes, please rinse immediately with plenty of water and seek medical advice.

People can use the following data to convert to the molecule structure.
(1)SMILES:Clc1cc(C(=O)OC)c(N)cc1
(2)InChI:InChI=1/C8H8ClNO2/c1-12-8(11)6-4-5(9)2-3-7(6)10/h2-4H,10H2,1H3
(3)InChIKey:IGHVUURTQGBABT-UHFFFAOYAW
(4)Std. InChI:InChI=1S/C8H8ClNO2/c1-12-8(11)6-4-5(9)2-3-7(6)10/h2-4H,10H2,1H3
(5)Std. InChIKey:IGHVUURTQGBABT-UHFFFAOYSA-N