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Methyldiphenylphosphine

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Name

Methyldiphenylphosphine

EINECS 216-065-5
CAS No. 1486-28-8 Density 1.076 g/mL at 25 °C(lit.)
PSA 13.59000 LogP 2.74910
Solubility Insoluble in water. Melting Point 117-118 °C
Formula C13H13P Boiling Point 308.1 °C at 760 mmHg
Molecular Weight 200.22 Flash Point 128.4 °C
Transport Information N/A Appearance Colorless to light yellow liquid
Safety 17-23-24/25-36/37/39-26 Risk Codes 36/37/38-20/21/22
Molecular Structure Molecular Structure of 1486-28-8 (Methyldiphenylphosphine) Hazard Symbols HarmfulXn
Synonyms

Diphenylmethylphosphine;Diphenylphosphinomethane;Methyldiphenylphosphine;NSC 158476;

Article Data 89

Methyldiphenylphosphine Synthetic route

{Cp(PMePh2)2molybdenum(III) dichloride}

594-09-2

trimethylphosphane

cyclopentadienylmolybdenum(III)(PMe3)2Cl2

B

1486-28-8

diphenyl(methyl)phosphine

Conditions
ConditionsYield
In toluene mixing of the Mo compd. with the free phosphine (molar ratio 2.1:1) in toluene;;A 100%
B n/a

{Cp(PMePh2)2molybdenum(III) dichloride}

554-70-1

triethylphosphine

{Cp(PEt3)2molybdenum(III) dichloride}

B

1486-28-8

diphenyl(methyl)phosphine

Conditions
ConditionsYield
In toluene mixing of the Mo compd. with the free phosphine (molar ratio 2.0:1) in toluene;;A 100%
B n/a

{Cp(PMePh2)2molybdenum(III) dichloride}

672-66-2

Dimethyl(phenyl)phosphine

{Cp(PMe2Ph)2molybdenum(III) dichloride}

B

1486-28-8

diphenyl(methyl)phosphine

Conditions
ConditionsYield
In toluene mixing of the Mo compd. with the free phosphine (molar ratio 2.0:1) in toluene;;A 100%
B n/a

{Cp(PMePh2)2molybdenum(III) dichloride}

1663-45-2

1,2-bis-(diphenylphosphino)ethane

cyclopentadienylmolybdenum(III)(bis(diphenylphosphino)ethane)Cl2

B

1486-28-8

diphenyl(methyl)phosphine

Conditions
ConditionsYield
In dichloromethane mixing of the Mo compd. with the free phosphine (molar ratio 1.1:1) inCH2Cl2;;A 100%
B n/a
2129-89-7

diphenyl(methyl)phosphine oxide

1486-28-8

diphenyl(methyl)phosphine

Conditions
ConditionsYield
With lithium aluminium tetrahydride; cerium(III) chloride In tetrahydrofuran at 40℃; for 0.5h;98%
With aluminium hydride*tetrahydrofuran In tetrahydrofuran for 0.5h; Heating;96%
Stage #1: diphenyl(methyl)phosphine oxide With trityl tetrakis(pentafluorophenyl)borate In (2)H8-toluene at 20℃; Glovebox; Inert atmosphere;
Stage #2: With phenylsilane In (2)H8-toluene at 80℃; for 1.5h; Glovebox; Inert atmosphere; Sealed tube;
93%
13683-01-7

Diphenylphosphonigsaeure-trimethylsilylester

917-54-4

methyllithium

1486-28-8

diphenyl(methyl)phosphine

Conditions
ConditionsYield
In tetrahydrofuran at 0 - 25℃; for 2h;96%

Ph2PCH2NHPh

74-88-4

methyl iodide

1486-28-8

diphenyl(methyl)phosphine

Conditions
ConditionsYield
Stage #1: Ph2PCH2NHPh With methyllithium In toluene at -78 - 20℃; Inert atmosphere;
Stage #2: methyl iodide In toluene at -78℃; Inert atmosphere;
95%
693-03-8

n-butyl magnesium bromide

75-16-1

methylmagnesium bromide

119841-34-8, 127780-84-1

cis-2,10-dimethyl-<1,2,3>benzothiadiphospholo<2,3-b><1,2,3>benzothiadiphosphole

phenylmagnesium bromide

A

33374-48-0

dibutyl-methyl-phosphine

B

36050-91-6, 36850-51-8, 36850-52-9

n-Butyl-methyl-phenyl-phosphin

C

1486-28-8

diphenyl(methyl)phosphine

D

736137-64-7

4-methyl-2-[(5-methyl-2-sulfanylphenyl)phosphanyl]benzenethiol

Conditions
ConditionsYield
Stage #1: n-butyl magnesium bromide; cis-2,10-dimethyl-<1,2,3>benzothiadiphospholo<2,3-b><1,2,3>benzothiadiphosphole; phenylmagnesium bromide In tetrahydrofuran for 0.0833333h;
Stage #2: methylmagnesium bromide In tetrahydrofuran Title compound not separated from byproducts;
A n/a
B n/a
C n/a
D 90%
75-16-1

methylmagnesium bromide

925-90-6

ethylmagnesium bromide

119841-34-8, 127780-84-1

cis-2,10-dimethyl-<1,2,3>benzothiadiphospholo<2,3-b><1,2,3>benzothiadiphosphole

phenylmagnesium bromide

A

1605-58-9

diethylmethylphosphine

B

15849-84-0, 52119-19-4, 72974-35-7

ethylmethylphenylphosphine

C

1486-28-8

diphenyl(methyl)phosphine

D

736137-64-7

4-methyl-2-[(5-methyl-2-sulfanylphenyl)phosphanyl]benzenethiol

Conditions
ConditionsYield
Stage #1: ethylmagnesium bromide; cis-2,10-dimethyl-<1,2,3>benzothiadiphospholo<2,3-b><1,2,3>benzothiadiphosphole; phenylmagnesium bromide In tetrahydrofuran for 0.0833333h;
Stage #2: methylmagnesium bromide In tetrahydrofuran Title compound not separated from byproducts;
A n/a
B n/a
C n/a
D 90%
126140-10-1

Ph2PCH2NH(t-Bu)

74-88-4

methyl iodide

1486-28-8

diphenyl(methyl)phosphine

Conditions
ConditionsYield
Stage #1: Ph2PCH2NH(t-Bu) With methyllithium In toluene at -78 - 20℃; Inert atmosphere;
Stage #2: methyl iodide In toluene at -78℃; Inert atmosphere;
89%

Methyldiphenylphosphine Specification

The Methyldiphenylphosphine is an organic compound with the formula C13H13P. The systematic name of this chemical is Methyl(diphenyl)phosphane. With the CAS registry number 1486-28-8, it is also named as Diphenyl-methylphosphine. The product's categories are Ligand; Phosphine Ligands; Synthetic Organic Chemistry. Besides, its molecular weight is colorless to light yellow liquid, which should be stored in a cool, sealed, dry, well-ventilated, lightproof place.

Physical properties about Methyldiphenylphosphine are: (1)ACD/LogP: 4.32; (2)ACD/LogD (pH 5.5): 4.32; (3)ACD/LogD (pH 7.4): 4.32; (4)ACD/BCF (pH 5.5): 1134.76; (5)ACD/BCF (pH 7.4): 1134.76; (6)ACD/KOC (pH 5.5): 5349.33; (7)ACD/KOC (pH 7.4): 5349.33; (8)#Freely Rotating Bonds: 2; (9)Polar Surface Area: 13.59 Å2; (10)Flash Point: 128.4 °C; (11)Enthalpy of Vaporization: 52.68 kJ/mol; (12)Boiling Point: 308.1 °C at 760 mmHg; (13)Vapour Pressure: 0.00127 mmHg at 25 °C.

When you are using this chemical, please be cautious about it as the following:
It is harmful by inhalation, in contact with skin and if swallowed. Besides, this chemical is irritating to eyes, respiratory system and skin. When you are using it, keep away from combustible material, and do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer). And you should avoid contact with skin and eyes and wear suitable protective clothing, gloves and eye/face protection when you are using it. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)InChI: InChI=1/C13H13P/c1-14(12-8-4-2-5-9-12)13-10-6-3-7-11-13/h2-11H,1H3
(2)InChIKey: UJNZOIKQAUQOCN-UHFFFAOYAL
(3)Std. InChI: InChI=1S/C13H13P/c1-14(12-8-4-2-5-9-12)13-10-6-3-7-11-13/h2-11H,1H3
(4)Std. InChIKey: UJNZOIKQAUQOCN-UHFFFAOYSA-N

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