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Miglitol

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Name

Miglitol

EINECS 276-661-6
CAS No. 72432-03-2 Density 1.458 g/cm3
PSA 104.39000 LogP -3.32420
Solubility Soluble Melting Point 114 °C
Formula C8H17NO5 Boiling Point 453.7 °C at 760 mmHg
Molecular Weight 207.227 Flash Point 284.3 °C
Transport Information N/A Appearance white to light yellow crystal powder
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 72432-03-2 (Miglitol) Hazard Symbols N/A
Synonyms

3,4,5-Piperidinetriol,1-(2-hydroxyethyl)-2-(hydroxymethyl)-, [2R-(2a,3b,4a,5b)]-;BAY 1099;BAY-m 1099;Diastabol;Glyset;3,4,5-Piperidinetriol,1-(2-hydroxyethyl)-2-(hydroxymethyl)-, (2R,3R,4R,5S)-;

Article Data 11

Miglitol Synthetic route

72432-03-2

miglitol

100-52-7

benzaldehyde

1194233-02-7

C15H21NO5

Conditions
ConditionsYield
With zinc(II) chloride at 50℃; for 48h;90%

Miglitol Chemical Properties

Structure of Miglitol (CAS NO.72432-03-2):

IUPAC Name: (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol 
Empirical Formula: C8H17NO5
Molecular Weight: 207.2243 
EINECS: 276-661-6 
Index of Refraction: 1.597
Molar Refractivity: 48.48 cm3
Molar Volume: 142.1 cm3
Polarizability: 19.22×10-24cm3
Surface Tension: 79.2 dyne/cm
Density: 1.458 g/cm3
Flash Point: 284.3 °C
Enthalpy of Vaporization: 82.27 kJ/mol 
Melting Point: 114°C
Boiling Point: 453.7 °C at 760 mmHg
Vapour Pressure: 3.87E-10 mmHg at 25°C 
Water Solubility: Soluble 
Physical Appearance: white to light yellow crystal powder
Product Categories: Antidiabetic;Diabetes;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals

Miglitol Uses

 Miglitol (CAS NO.72432-03-2) is an oral anti-diabetic drug .Its  acts by inhibiting the ability of the patient to breakdown complex carbohydrates into glucose. It is primarily used in diabetes mellitus type 2 for establishing greater glycemic control by preventing the digestion of carbohydrates (such as disaccharides and polysaccharides,etc) into monosaccharides which can be absorbed by the body.

Miglitol Specification

  Miglitol , its cas register number is 72432-03-2. It also can be called (2R,3R,4R,5S)-1-(2-Hydroxyethyl)-2-(hydroxymethyl)-3,4,5-piperidinetriol ; 3,4,5-Piperidinetriol, 1-(2-hydroxyethyl)-2-(hydroxymethyl)-, (2R-(2alpha,3beta,4alpha,5beta))- ; Bay 1099 ; Bay m 1099 ; Glyset ; Miglitolum ; N-(2-Hydroxyethyl)-1-deoxynojirimycin .

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