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N-(2-Hydroxyethyl)ethylenediaminetriacetic acid

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Name

N-(2-Hydroxyethyl)ethylenediaminetriacetic acid

EINECS 205-759-3
CAS No. 150-39-0 Density 1.468 g/cm3
PSA 138.61000 LogP -2.16350
Solubility soluble Melting Point 212 °C (dec.)(lit.)
Formula C10H18N2O7 Boiling Point 572.5 °C at 760 mmHg
Molecular Weight 278.262 Flash Point 300 °C
Transport Information N/A Appearance White crystalline powder
Safety 26-37/39-36-22 Risk Codes 36/37/38-22-40-20/21/22
Molecular Structure Molecular Structure of 150-39-0 (N-(2-Hydroxyethyl)ethylenediaminetriacetic acid) Hazard Symbols HarmfulXn, IrritantXi
Synonyms

Glycine,N-(carboxymethyl)-N'-(2-hydroxyethyl)-N,N'-ethylenedi- (8CI);(2-Hydroxyethyl)ethylenediaminetriacetic acid;Chel DM Acid;(Hydroxyethyl)ethylenediaminetriacetic acid;Hamp-OL;Hydroxyethylethylenediaminotriacetic acid;N-(2-Hydroxyethyl)ethylenediamine-N,N',N'-triacetic acid;N-(Hydroxyethyl)ethylenediamine-N,N',N'-triacetic acid;N-(Hydroxyethyl)ethylenediaminetriacetic acid;NSC 7341;N'-(2-Hydroxyethyl)ethylenediamine-N,N,N'-triacetic acid;Oxyethylethylenediaminetriacetic acid;HEDTA;HEEDTA;Detarol;DissolvineH;

Article Data 7

N-(2-Hydroxyethyl)ethylenediaminetriacetic acid Synthetic route

50-00-0

formaldehyd

143-33-9

sodium cyanide

111-41-1

2-(2-Aminoethylamino)ethanol

150-39-0

N-(2-hydroxyethyl)ethylenediaminetriacetic acid

Conditions
ConditionsYield
With sodium hydroxide

Fe(3+)*3ClO4(1-)*7H2O=[Fe(ClO4)3]*7H2O

150-39-0

N-(2-hydroxyethyl)ethylenediaminetriacetic acid

[Fe(III)(N-hydroxyethyl-ethylenediamine triacetate)(H2O)]

Conditions
ConditionsYield
In water a ligand (0.01 mol) was suspended in water; the Fe-contg. compd. (0.01 mol) was added with stirring; acetone was added; the crystals were pptd. overnighnt being placed in a refrigerator; elem. anal.;89%
150-39-0

N-(2-hydroxyethyl)ethylenediaminetriacetic acid

7718-98-1

vanadium(III) chloride

497-19-8

sodium carbonate

{N'-(2-hydroxyethyl)ethylenediamine-N,N,N'-triacetato}aquavanadium(III)*2H2O

Conditions
ConditionsYield
In water under N2; ligand in H2O neutralized with Na2CO3; anhydrous VCl3 added, soln. stirred for a few minutes; crystals collected, washed with cold water and acetone; elem. anal.;85%

malachite

150-39-0

N-(2-hydroxyethyl)ethylenediaminetriacetic acid

205673-75-2

[(N-(2-hydroxyethyl)-N'-carboxymethyl-1,2-ethylenediamine-N,N'-diacetato)copper(II) hydrate]

Conditions
ConditionsYield
In water byproducts: CO2, CuO; N-(2-hydroxyethyl)-1,2-ethylenediamine-N,N,N'-triacetic acid and Cu2CO3(OH)2 in water heated in a Kitasato-flask (t<50 °C), stirred at reduced pressure to remove CO2, then heated at 60 °C, stirred 30 min, cooled to room temp.; filtered, slow evapn. of solvent in 3-4 wk, crystn., filtered, washed with cold water, air-dried, recrystn. from hot water; elem. anal.;85%

samarium(III) carbonate

150-39-0

N-(2-hydroxyethyl)ethylenediaminetriacetic acid

Sm(3+)*C10H15N2O7(3-)*5H2O=Sm(C10H15N2O7)*5H2O

Conditions
ConditionsYield
With water In water in hot soln.; addn. of isopropanol with vigorous shaking then addn. of alcohol, washing (isopropanol), drying in air (24 h);80%

yttrium(III) carbonate

150-39-0

N-(2-hydroxyethyl)ethylenediaminetriacetic acid

Y(3+)*C10H15N2O7(3-)*6H2O=Y(C10H15N2O7)*6H2O

Conditions
ConditionsYield
With water In water in hot soln.; addn. of isopropanol with vigorous shaking then addn. of alcohol, washing (isopropanol), drying in air (24 h);80%

neodymium carbonate

150-39-0

N-(2-hydroxyethyl)ethylenediaminetriacetic acid

Nd(3+)*C10H15N2O7(3-)*6H2O=Nd(C10H15N2O7)*6H2O

Conditions
ConditionsYield
With water In water in hot soln.; addn. of isopropanol with vigorous shaking then addn. of alcohol, washing (isopropanol), drying in air (24 h);80%

gadolinium(III) carbonate

150-39-0

N-(2-hydroxyethyl)ethylenediaminetriacetic acid

Gd(3+)*C10H15N2O7(3-)*6H2O=Gd(C10H15N2O7)*6H2O

Conditions
ConditionsYield
With water In water in hot soln.; addn. of isopropanol with vigorous shaking then addn. of alcohol, washing (isopropanol), drying in air (24 h);80%

europium(III) carbonate

150-39-0

N-(2-hydroxyethyl)ethylenediaminetriacetic acid

Eu(3+)*C10H15N2O7(3-)*5H2O=Eu(C10H15N2O7)*5H2O

Conditions
ConditionsYield
With water In water in hot soln.; addn. of isopropanol with vigorous shaking then addn. of alcohol, washing (isopropanol), drying in air (24 h);80%

thorium(IV) nitrate pentahydrate

150-39-0

N-(2-hydroxyethyl)ethylenediaminetriacetic acid

1310-73-2

sodium hydroxide

Th6(N-(2-hydroxoethyl)ethylenediaminetriacetate)

Conditions
ConditionsYield
In water for 48h; pH=8.4;72.1%

N-(2-Hydroxyethyl)ethylenediaminetriacetic acid Chemical Properties

Molecular Formula: C10H18N2O7
Molecular Weight:
278.260 g/mol 
EINECS: 205-759-3
Water Solubility: Soluble
Flash Point: 300 °C
Density: 1.468 g/cm3
Index of Refraction: 1.568 
Melting Point: 212-214 °C 
Enthalpy of Vaporization: 98.57 kJ/mol  
Vapour Pressure: 1.72E-15 mmHg at 25 °C
Boiling Point: 572.5 °C at 760 mmHg
The molecular structure of N-(2-Hydroxyethyl)ethylenediaminetriacetic acid (CAS NO.150-39-0): 
                                        
IUPAC: 2-[2-[Bis(carboxymethyl)amino]ethyl-(2-hydroxyethyl)amino]acetic acid
Product Category of N-(2-Hydroxyethyl)ethylenediaminetriacetic acid (CAS NO.150-39-0): Analytical Chemistry;Chelating Reagents;Complexones;EDTA Analogs

N-(2-Hydroxyethyl)ethylenediaminetriacetic acid Uses

 N-(2-Hydroxyethyl)ethylenediaminetriacetic acid (CAS NO.150-39-0) can be used not as a binder, but also for the textile, pharmaceutical industries and rare element of the refining.

N-(2-Hydroxyethyl)ethylenediaminetriacetic acid Toxicity Data With Reference

1.    

ipr-rat LD50:337 mg/kg

    AHRTAN    Arhiv za Higijenu Rada i Toksikologiju. Archives of Industrial Hygiene and Toxicology. 13 (1962),295.
2.    

ipr-mus LD50:259 mg/kg

    ARTODN    Archives of Toxicology. 57 (1985),212.

N-(2-Hydroxyethyl)ethylenediaminetriacetic acid Consensus Reports

Reported in EPA TSCA Inventory.

N-(2-Hydroxyethyl)ethylenediaminetriacetic acid Safety Profile

Poison by intraperitoneal route. When heated to decomposition it emits toxic fumes such as NOx.
Hazard Symbols:Xn:
Risk Codes: R22;R36/37/38 
R22: Harmful if swallowed
R36/37/38 : Irritating to eyes, respiratory system and skin
Safety Description: S26;S37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical
advice
S37/39 : Wear suitable gloves and eye/face protection

N-(2-Hydroxyethyl)ethylenediaminetriacetic acid Specification

  N-(2-Hydroxyethyl)ethylenediaminetriacetic acid , its cas register number is 150-39-0. It also can be called N-Carboxymethyl-N'-(2-hydroxyethyl)-N,N'-ethylenediglycine ; N-(2-Hydroxyethyl)ethylenediamine-N,N',N'-triacetic acid and HEDTA .

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