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Cas Database |
| Name |
N-Hydroxyphenacetin |
EINECS | N/A |
| CAS No. | 19315-64-1 | Density | 1.2g/cm3 |
| PSA | 49.77000 | LogP | 1.82740 |
| Solubility | N/A | Melting Point |
N/A |
| Formula | C10H13 N O3 | Boiling Point | 345.5°Cat760mmHg |
| Molecular Weight | 195.218 | Flash Point | 162.7°C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Moderately toxic by intraperitoneal route. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Acetohydroxamicacid, N-(p-ethoxyphenyl)- (8CI); 4'-Ethoxy-N-hydroxyacetanilide;N-(4-Ethoxyphenyl)-N-hydroxyacetamide; N-Hydroxy-p-acetophenetidide;N-Hydroxyphenacetin; NSC 229647 |
Article Data | 5 |
N-Hydroxyphenacetin Chemical Properties
Empirical Formula of N-Hydroxyphenacetin (CAS NO.19315-64-1): C10H13NO3
Molecular Weight: 195.2151
Index of Refraction: 1.571
Density: 1.2 g/cm3
Flash Point: 162.7 °C
Enthalpy of Vaporization: 62.22 kJ/mol
Boiling Point: 345.5 °C at 760 mmHg
Vapour Pressure: 2.33E-05 mmHg at 25 °C
Structure of N-Hydroxyphenacetin (CAS NO.19315-64-1):
IUPAC Name: N-(4-Ethoxyphenyl)-N-hydroxyacetamide
Canonical SMILES: CCOC1=CC=C(C=C1)N(C(=O)C)O
InChI: InChI=1S/C10H13NO3/c1-3-14-10-6-4-9(5-7-10)11(13)8(2)12/h4-7,13H,3H2,1-2H3
InChIKey: GPMYDZBSYQUDJZ-UHFFFAOYSA-N
N-Hydroxyphenacetin Toxicity Data With Reference
| 1. | mma-sat 500 µg/plate | MUREAV Mutation Research. 58 (1978),387. | ||
| 2. | otr-mus:emb 100 µg/L | NCIMAV National Cancer Institute, Monograph. 58 (1981),21. | ||
| 3. | ipr-mus LD50:702 mg/kg | ARTODN Archives of Toxicology. 56 (1984),96. |
N-Hydroxyphenacetin Consensus Reports
IARC Cancer Review: Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 13 , 1977,p. 141.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 24 , 1980,p. 135.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .
N-Hydroxyphenacetin Safety Profile
Moderately toxic by intraperitoneal route. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition N-Hydroxyphenacetin (CAS NO.19315-64-1) emits toxic fumes of NOx.
N-Hydroxyphenacetin Specification
N-Hydroxyphenacetin , its cas register number is 19315-64-1. It also can be called Acetohydroxamic acid, N-(4-ethoxyphenyl)- ; p-Acetophenetidide, N-hydroxy- ; Acetohydroxamic acid, N-(p-ethoxyphenyl)- (8CI) ; and N-Hydroxy-p-acetophenetidide .
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