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Cas Database |
| Name |
Pachycarpine |
EINECS | N/A |
| CAS No. | 492-08-0 | Density | 1.08g/cm3 |
| PSA | 6.48000 | LogP | 2.22090 |
| Solubility | N/A | Melting Point |
201oC |
| Formula | C15H26N2 | Boiling Point | 340.9°Cat760mmHg |
| Molecular Weight | 234.385 | Flash Point | 148.3°C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Poison by subcutaneous and intravenous routes. When heated to decomposition it emits toxic fumes of NOx. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Pachycarpine; |
Article Data | 13 |
Pachycarpine Chemical Properties
Chemistry informtion about Pachycarpine (CAS NO.492-08-0) is:
Synonyms: Pachycarpine ; (1r,2s,9r,10r)-7,15-Diazatetracyclo[7.7.1.02,7.010,15]Heptadecane ; (7r)-1,3,4,7,7aβ,8,9,10,11,13,14,14aα-Dodecahydro-7β,14β-Methano-2h,6h-Dipyrido[1,2-A:1',2'-E][1,5]Diazocine ; D-Sparteine ; Sparteine D-Isomer
MF: C15H26N2
MW: 234.38
Density: 1.08 g/cm3
Flash Point: 148.3 °C
Boiling Point: 340.9 °C at 760 mmHg
Vapour Pressure: 8.34E-05 mmHg at 25°C
Enthalpy of Vaporization: 58.45 kJ/mol
Following is the molecular structure of Pachycarpine (CAS NO.492-08-0) is:
Pachycarpine Uses
Pachycarpine (CAS NO.492-08-0) has been used as an oxytocic and an anti-arrhythmia agent. It has also been of interest because of genetic variation in its metabolism.
Pachycarpine Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 89100ug/kg (89.1mg/kg) | behavioral: tremor behavioral: convulsions or effect on seizure threshold lungs, thorax, or respiration: dyspnea | Shaanxi Xinyiyao. Shaanxi New Medical. Vol. 11(6), Pg. 53, 1982. |
| mouse | LD50 | intravenous | 26mg/kg (26mg/kg) | "Ganglion-Blocking and Ganglion-Stimulation Agents," Kharkevich, D.A., Moscow, First Moscow Medical Institute, 1967Vol. -, Pg. 175, 1967. | |
| mouse | LD50 | subcutaneous | 90mg/kg (90mg/kg) | behavioral: muscle contraction or spasticity) lungs, thorax, or respiration: dyspnea | Farmakologiya i Toksikologiya Vol. 21(5), Pg. 46, 1958. |
Pachycarpine Safety Profile
Poison by subcutaneous and intravenous routes. When heated to decomposition it emits toxic fumes of NOx.
Pachycarpine Specification
Pachycarpine (CAS NO.492-08-0) is an alkaloid isolated from lupin beans, Lupinus luteus and Lupinus niger.
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