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Name |
Perhexiline maleate |
EINECS | N/A |
CAS No. | 6724-53-4 | Density | N/A |
PSA | 86.63000 | LogP | 5.33600 |
Solubility | N/A | Melting Point |
181-183°C |
Formula | C19H35N•C4H4O4 | Boiling Point | 574.1°C at 760 mmHg |
Molecular Weight | 393.567 | Flash Point | 301°C |
Transport Information | N/A | Appearance | N/A |
Safety | Poison by intraperitoneal route. Moderately toxic by ingestion. Human systemic effects by ingestion: muscle weakness, paresthesia, and hepatitis. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. | Risk Codes | N/A |
Molecular Structure | Hazard Symbols | N/A | |
Synonyms |
2-[2,2-DICYCLOHEXYLETHYL]PIPERIDINE MALEATE SALT;PERHEXILINE MALEATE SALT;2-(2,2-dicyclohexylethyl)piperidinemaleate;2-(2,2-dicyclohexylethyl)-piperidinmaleate(1:1);perhexilinemaleate;2-(2,2-dicyclohexylethyl)piperidinium hydrogen maleate;perhexilene maleate |
Article Data | 2 |
IUPAC Name: (Z)-But-2-enedioic acid ; 2-(2,2-Dicyclohexylethyl)piperidine
Synonyms: 1,1-Dicyclohexyl-2-(2-piperidyl)ethane Maleate ; 2-(2,2-Dicyclohexylethyl)piperidine (2Z)-2-butenedioate (1:1) ; 2-(2,2-Dicyclohexylethyl)piperidine (2Z)-but-2-enedioate (1:1) ; Piperidine, 2-(2,2-dicyclohexylethyl)-, (2Z)-2-butenedioate (1:1)
CAS NO: 6724-53-4
Molecular Formula of Perhexiline maleate (CAS NO.6724-53-4) : C23H39NO4
Molecular Weight of Perhexiline maleate (CAS NO.6724-53-4) : 393.56
Molecular Structure of Perhexiline maleate (CAS NO.6724-53-4) :
EINECS: 229-775-5
Flash Point: 164.5 °C
Enthalpy of Vaporization: 58.35 kJ/mol
Boiling Point: 340 °C at 760 mmHg
Vapour Pressure: 8.88E-05 mmHg at 25°C
Perhexiline maleate (CAS NO.6724-53-4) is used for angina and arrhythmia.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
man | LDLo | oral | 4693mg/kg/3Y (4693mg/kg) | BEHAVIORAL: MUSCLE WEAKNESS LIVER: "HEPATITIS, FIBROUS (CIRRHOSIS, POST-NECROTIC SCARRING)" | New Zealand Medical Journal. Vol. 96, Pg. 202, 1983. |
man | TDLo | oral | 636mg/kg/89D- (636mg/kg) | LIVER: "JAUNDICE, OTHER OR UNCLASSIFIED" SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" | British Journal of Clinical Practice. Vol. 31, Pg. 136, 1977. |
mouse | LD50 | intraperitoneal | 107mg/kg (107mg/kg) | BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Oyo Yakuri. Pharmacometrics. Vol. 21, Pg. 83, 1981. |
mouse | LD50 | oral | 2641mg/kg (2641mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA | Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 337, 1977. |
mouse | LD50 | subcutaneous | > 2gm/kg (2000mg/kg) | SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Oyo Yakuri. Pharmacometrics. Vol. 21, Pg. 83, 1981. |
rat | LD50 | intraperitoneal | 106mg/kg (106mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Oyo Yakuri. Pharmacometrics. Vol. 21, Pg. 83, 1981. |
rat | LD50 | oral | 2150mg/kg (2150mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA | Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 337, 1977. |
rat | LD50 | subcutaneous | > 2gm/kg (2000mg/kg) | SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Oyo Yakuri. Pharmacometrics. Vol. 21, Pg. 83, 1981. |
Poison by intraperitoneal route. Moderately toxic by ingestion. Human systemic effects by ingestion: muscle weakness, paresthesia, and hepatitis. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
WGK Germany 2
RTECS TM7068000