1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole

Base Information

• Chemical Name: 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole
• CAS No.: 289905-88-0
• Molecular Formula: C₂₂H₁₇ClN₂
• Molecular Weight: 344.843
• Hs Code.: 2933199090
• European Community (EC) Number: 625-808-6
• DSSTox Substance ID: DTXSID70349650
• Nikkaji Number: J1.388.964C
• Wikidata: Q27089017
• Pharos Ligand ID: M5ZY799ZP6WG
• Metabolomics Workbench ID: 70002
• ChEMBL ID: CHEMBL498270
• Mol file: 289905-88-0.mol

Synonyms:1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole;TRAM 34;TRAM-34

Chemical Property of 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole

Chemical Property:

• Vapor Pressure: 5.04E-10mmHg at 25°C
• Melting Point: 145-147oC
• Boiling Point: 510.2oC at 760 mmHg
• Flash Point: 262.4oC
• PSA: 17.82000
• Density: 1.13g/cm3
• LogP: 5.37670
• Storage Temp.: 2-8°C
• Solubility.: DMSO: ~11 mg/mL
• Water Solubility.: Soluble in DMSO at 2mg/ml. Insoluble in water
• XLogP3: 5.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 344.1080262
• Heavy Atom Count: 25
• Complexity: 396

Purity/Quality:

98%,99%, ^*data from raw suppliers

TRAM 34 ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CC=N4
• Uses: TRAM-34 blocks intermediate conductance calcium-activated potassium channel IKCa1 with a Kd of 20nM and exhibits exquisite selectivity for the channel. Clotrimazole impurity.

Technology Process of 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole

There total 1 articles about 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ clotrimazole (289905-88-0)

Guidance literature:

Refernces