3-phenylnaphthalen-1-ol

Base Information

• Chemical Name: 3-phenylnaphthalen-1-ol
• CAS No.: 30069-65-9
• Molecular Formula: C16H12O
• Molecular Weight: 220.271
• Mol file: 30069-65-9.mol

Synonyms:3-Phenyl-[1]naphthol;4-Oxy-2-phenyl-naphthalin;3-phenyl-1-naphthol;

Chemical Property of 3-phenylnaphthalen-1-ol

Chemical Property:

• Melting Point: 96-97.5 °C(Solv: chloroform (67-66-3); hexane (110-54-3))
• Boiling Point: 417.4±24.0 °C(Predicted)
• PKA: 9.28±0.40(Predicted)
• PSA: 20.23000
• Density: 1.176±0.06 g/cm3(Predicted)
• LogP: 4.21240

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-Phenylnaphthalen-1-ol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-phenylnaphthalen-1-ol

There total 40 articles about 3-phenylnaphthalen-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2-(2-acetylphenyl)-1-phenylethan-1-one (53067-92-8) → 3-phenylnaphthalen-1-ol (30069-65-9)

Guidance literature:

2-(2-acetylphenyl)-1-phenylethan-1-one; With potassium hydroxide; In methanol; at 20 ℃; for 1h; Inert atmosphere;

With ammonium chloride; In methanol; water; Saturated solution;

DOI:10.1021/ja2108992

Reference yield: 92.0%

1,3-dihydroxynaphthalene (132-86-5) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → 3-phenylnaphthalen-1-ol (30069-65-9)

Guidance literature:

With hydrogen fluoride; antimony pentafluoride; at -20 ℃; for 5h;

Reference yield: 91.0%

1-(2-methylphenyl)-3-phenylprop-2-yn-1-one (172264-69-6) → 3-phenylnaphthalen-1-ol (30069-65-9)

Guidance literature:

With copper(II) bis(trifluoromethanesulfonate); In tetrahydrofuran; at 20 ℃; for 24h; Irradiation; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.orglett.0c01854

upstream raw materials:

3,4-diphenyl-crotonic acid

bromobenzene

(E)-N,N-diethyl-3-phenylbut-2-enamide

3,4-dihydro-3-cyano-3-phenyl-1H-2-benzopyran-1-one

Downstream raw materials:

2-phenyl[1,4]naphthoquinone

3-phenylnaphthalene-1,2-dione

2-phenylnaphthalene

<3-Phenyl-naphthyl-(1)-oxy>-essigsaeure

Refernces

• 1、 Chen, Yuan,Fang, Siqiang,Pan, Jianke,Ren, Xiaoyu,Tan, Jian-Ping,Wang, Tianli,Zhang, Hongkui. "Enantiodivergent Kinetic Resolution of 1,1′-Biaryl-2,2′-Diols and Amino Alcohols by Dipeptide-Phosphonium Salt Catalysis Inspired by the Atherton–Todd Reaction". supporting information. p. 14921 - 14930. Retrieved 2021/05/10.
• 2、 -. "AMINE-SUBSTITUTED NAPHTHALENE DERIVATIVES AND ORGANIC LIGHT EMITTING DIODES INCLUDING THE SAME". Paragraph 0066-0067. . Retrieved 2019/05/18.