Ethylhydrazine hydrochloride

Base Information

• Chemical Name: Ethylhydrazine hydrochloride
• CAS No.: 18413-14-4
• Molecular Formula: C2H8 N2 . Cl H
• Molecular Weight: 96.5599
• Hs Code.: 2928000090
• UNII: X9EZ1T7X9Q
• DSSTox Substance ID: DTXSID0020608
• Wikidata: Q27293728
• Mol file: 18413-14-4.mol

Synonyms:ethylhydrazine;ethylhydrazine hydrochloride

Chemical Property of Ethylhydrazine hydrochloride

Chemical Property:

• Vapor Pressure: 26.6mmHg at 25°C
• Boiling Point: 107.9°Cat760mmHg
• Flash Point: 15.7°C
• PSA: 38.05000
• Density: g/cm³
• LogP: 1.36280
• Storage Temp.: Inert atmosphere,Room Temperature
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 96.0454260
• Heavy Atom Count: 5
• Complexity: 8

Purity/Quality:

99% ^*data from raw suppliers

1-EthylhydrazineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCNN.Cl

Technology Process of Ethylhydrazine hydrochloride

There total 2 articles about Ethylhydrazine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

C8H19N4(1+)*I(1-) → ethylhydrazine hydrochloride salt (18413-14-4,49540-34-3)

Guidance literature:

With hydrogenchloride; potassium hydroxide; 1) reflux;

Reference yield: 63.0%

ethylmagnesium chloride (2386-64-3) → ethylhydrazine hydrochloride salt (18413-14-4,49540-34-3)

Guidance literature:

ethylmagnesium chloride; With dinitrogen monoxide; In tetrahydrofuran; for 3h; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; 1,4-dioxane; water; Inert atmosphere;

DOI:10.1021/om500333y

Reference yield: 95.0%

1,1,1-trifluoro-4-phenylbut-3-yn-2-one (58518-08-4) + ethylhydrazine hydrochloride salt (18413-14-4,49540-34-3) → 1-ethyl-5-phenyl-3-trifluoromethyl-1H-pyrazole

Guidance literature:

ethylhydrazine hydrochloride salt; With 1,8-diazabicyclo[5.4.0]undec-7-ene;

1,1,1-trifluoro-4-phenylbut-3-yn-2-one; for 24h; regioselective reaction;

DOI:10.1021/acs.joc.7b00774

upstream raw materials:

ethylmagnesium chloride

Downstream raw materials:

5-Butyl-4-(2'-cyano-biphenyl-4-ylmethyl)-2-ethyl-2H-pyrazole-3-carboxylic acid ethyl ester

1-ethyl-3,5-dimethylpyrazole

C₁₁H₁₂Cl₂N₄

C₁₂H₁₁N₃O₂

Refernces

• 1、 Zelenin, K. N.,Khrustalev, V. A.,Sergutina, V. P.. "1,1,4,4,-TETRAALKYLAMIDAZINES. SYNTHESIS OF MONOALKYLHYDRAZINES". . p. 244 - 247. Retrieved 2007/10/02.