CYCLOPENTANONE ETHYLENE KETAL

Base Information

• Chemical Name: CYCLOPENTANONE ETHYLENE KETAL
• CAS No.: 176-32-9
• Molecular Formula: C7H12O2
• Molecular Weight: 128.171
• Hs Code.: 2932999099
• Mol file: 176-32-9.mol

Synonyms:cyclopentanone ethyleneacetal;

Chemical Property of CYCLOPENTANONE ETHYLENE KETAL

Chemical Property:

• Vapor Pressure: 7.53mmHg at 25°C
• Melting Point: 150-155 °C
• Refractive Index: n20/D 1.448(lit.)
• Boiling Point: 54-55 °C35 mm Hg(lit.)
• Flash Point: 120 °F
• PSA: 18.46000
• Density: 1.03 g/mL at 25 °C(lit.)
• LogP: 1.30350

Purity/Quality:

99% ^*data from raw suppliers

1,4-DIOXASPIRO(4.4)NONANE Aldrich ^*data from reagent suppliers

Safty Information:

• Statements: 10
• Safety Statements: 16

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of CYCLOPENTANONE ETHYLENE KETAL

There total 6 articles about CYCLOPENTANONE ETHYLENE KETAL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

ethylene glycol (107-21-1) + cyclopentanone (120-92-3) → 1,4-dioxaspiro[4.4]nonane (176-32-9)

Guidance literature:

With salicylic acid resin supported FeCl₃; In benzene; at 90 - 104 ℃; for 2h;

Reference yield: 79.0%

oxirane (75-21-8,99932-75-9) + cyclopentanone (120-92-3) → 1,4-dioxaspiro[4.4]nonane (176-32-9)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; for 0.0333333h; Ambient temperature;

DOI:10.1021/jo00077a060

Reference yield:

oxirane (75-21-8,99932-75-9) + cyclopentanone (120-92-3) → 1,4-dioxane (123-91-1,28347-88-8,28347-91-3,39449-24-6,54841-74-6) + 1,4-dioxaspiro[4.4]nonane (176-32-9)

Guidance literature:

K₁₀; montmorillonite; In toluene; at 40 - 60 ℃; for 0.166667h; under 11251.1 Torr; Product distribution / selectivity; Inert atmosphere;

upstream raw materials:

ethylene glycol

cyclopentanone

oxirane

1-(trimethylsilyloxy)cyclopentene

Downstream raw materials:

1,4-dioxaspiro[4.6]undecane

cyclohexanone

cyclopentanone

2-Hydroxyethyl pentanoate

Refernces

• 1、 Ren, Yi-Ming,Cai, Chun. "A green procedure for the protection of carbonyl compounds catalyzed by iodine in ionic liquid". . p. 7110 - 7112. Retrieved 2008.
• 2、 Ingalsbe, Michelle L.,St. Denis, Jeffrey D.,Gleason, James L.,Savage, G. Paul,Priefer, Ronny. "Synthesis of a novel chiral cubane-based Schiff base ligand and its application in asymmetric nitro-aldol (Henry) reactions". . p. 98 - 102. Retrieved 2010.
• 3、 Collin, Diego E.,Jackman, Edward H.,Jouandon, Nicolas,Sun, Wei,Light, Mark E.,Harrowven, David C.,Linclau, Bruno. "Decagram Synthesis of Dimethyl 1,4-Cubanedicarboxylate Using Continuous-Flow Photochemistry". . p. 1307 - 1314. Retrieved 2021.
• 4、 Reddy,Reddy,Giridhar. "Eco-friendly Pt-Mo/ZrO2 solid acid catalyst for selective protection of carbonyl compounds". . p. 1819 - 1823. Retrieved 2001.
• 5、 -. "Green efficient synthesis of ketal under catalysis of ionic liquid TTPT". Paragraph 0041-0043. . Retrieved 2021/08/07.
• 6、 -. "Glucopyranosyl derivative and application thereof in medicines". Paragraph 0395; 0396; 0397; 0398. . Retrieved 2016/10/08.