Naphthalene, 2-(3-bromopropoxy)-

Base Information

• Chemical Name: Naphthalene, 2-(3-bromopropoxy)-
• CAS No.: 3245-62-3
• Molecular Formula: C13H13BrO
• Molecular Weight: 265.15
• Hs Code.: 2909309090
• Mol file: 3245-62-3.mol

Synonyms:

Chemical Property of Naphthalene, 2-(3-bromopropoxy)-

Chemical Property:

• Boiling Point: 373.5±25.0 °C(Predicted)
• PSA: 9.23000
• Density: 1.368±0.06 g/cm3(Predicted)
• LogP: 4.00360

Purity/Quality:

95% ^*data from raw suppliers

2-(3-BROMOPROPOXY)NAPHTHALENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Naphthalene, 2-(3-bromopropoxy)-

There total 4 articles about Naphthalene, 2-(3-bromopropoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

methanesulfonic acid 3-(naphthalen-2-oxy)-1-propyl ester (463934-08-9) → 2-(3-bromopropoxy)naphthalene (3245-62-3)

Guidance literature:

With potassium bromide; In Tetraethylene glycol; at 100 ℃; for 0.5h;

DOI:10.1002/anie.200903903

Reference yield: 71.0%

1,3-dibromo-propane (109-64-8) + β-naphthol (135-19-3) → 2-(3-bromopropoxy)naphthalene (3245-62-3)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 50 ℃; for 27h;

DOI:10.1002/anie.200461806

Reference yield: 45.0%

→ 2-(3-bromopropoxy)naphthalene (3245-62-3)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide;

upstream raw materials:

1,3-dibromo-propane

β-naphthol

methanesulfonic acid 3-(naphthalen-2-oxy)-1-propyl ester

1,4-dibromo-butane

Downstream raw materials:

2-(3-hydroxypropoxy)naphthalene

β-naphthol

2-(3-(4-iodo-3-methoxy-3-methylbutoxy)propoxy)-naphthalene

2,3-dihydro-1H-naphtho<2,1-b>pyran

Refernces

• 1、 Akguen,Balkan,Guenay,Erol,Boydag. "Some new 7-aryloxyalkyltheophyllines as bronchodilators". . p. 175 - 179. Retrieved 1997.
• 2、 Szczepańska, Katarzyna,Pockes, Steffen,Podlewska, Sabina,H?ring, Carina,Mika, Kamil,Latacz, Gniewomir,Bednarski, Marek,Siwek, Agata,Karcz, Tadeusz,Nagl, Martin,Bresinsky, Merlin,M?nnich, Denise,Seibel, Ulla,Kuder, Kamil J.,Kotańska, Magdalena,Stark, Holger,Elz, Sigurd,Kie?-Kononowicz, Katarzyna. "Structural modifications in the distal, regulatory region of histamine H3 receptor antagonists leading to the identification of a potent anti-obesity agent". supporting information. . Retrieved 2020/12/07.
• 3、 Lv, Min,Ma, Jingchun,Li, Qin,Xu, Hui. "Discovery of benzotriazole-azo-phenol/aniline derivatives as antifungal agents". supporting information. p. 181 - 187. Retrieved 2017/12/04.