[4-(4-Benzoylphenyl)phenyl](phenyl)methanone

Base Information

• Chemical Name: [4-(4-Benzoylphenyl)phenyl](phenyl)methanone
• CAS No.: 33090-29-8
• Molecular Formula: C26H18O2
• Molecular Weight: 362.428
• DSSTox Substance ID: DTXSID20405417
• Nikkaji Number: J1.241.539G
• Wikidata: Q82209958
• Mol file: 33090-29-8.mol

Synonyms:[4-(4-benzoylphenyl)phenyl](phenyl)methanone;(4'-BENZOYL-BIPHENYL-4-YL)-PHENYL-METHANONE;4,4'-dibenzoylbiphenyl;dibenzoyl biphenyl;33090-29-8;biphenyl-4,4'-diylbis(phenylmethanone);Oprea1_221644;Oprea1_686102;SCHEMBL197633;4,4'-dibenzoyl-1,1'-biphenyl;DTXSID20405417;MLNFAVZUSGIURZ-UHFFFAOYSA-N;AKOS004114644;BB 0221216;(4*-Benzoyl-biphenyl-4-yl)-phenyl-methanone

Chemical Property of [4-(4-Benzoylphenyl)phenyl](phenyl)methanone

Chemical Property:

• XLogP3: 6.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 362.130679813
• Heavy Atom Count: 28
• Complexity: 463

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)C(=O)C4=CC=CC=C4

Technology Process of [4-(4-Benzoylphenyl)phenyl](phenyl)methanone

There total 30 articles about [4-(4-Benzoylphenyl)phenyl](phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

(4-bromophenyl)(phenyl)methanone (90-90-4) → 4,4'-dibenzoyl-1,1'-biphenyl (33090-29-8)

Guidance literature:

With ethylenediaminetetraacetic acid; potassium carbonate; ascorbic acid; In ethanol; water; for 7.5h; Heating;

DOI:10.1016/j.tetlet.2006.08.056

Reference yield: 62.5%

iron pentacarbonyl (13463-40-6,37220-42-1) + 4,4'-diiodobiphenyl (3001-15-8) + phenylboronic acid (98-80-6) → 4,4'-dibenzoyl-1,1'-biphenyl (33090-29-8) + (4'-iodobiphenyl-4-yl)(phenyl)methanone (1537180-47-4)

Guidance literature:

With bis-(1,3-dihydro-1,3-dimethyl-2H-imidazol-2-ylidene)diiodopalladium; potassium carbonate; at 80 ℃; for 24h; Inert atmosphere;

DOI:10.1002/bkcs.10904

Reference yield: 62.5%

iron pentacarbonyl (13463-40-6,71564-23-3,37220-42-1) + 4,4'-diiodobiphenyl (3001-15-8) + phenylboronic acid (98-80-6) → 4,4'-dibenzoyl-1,1'-biphenyl (33090-29-8) + (4'-iodobiphenyl-4-yl)(phenyl)methanone (1537180-47-4)

Guidance literature:

With Bis-(1,3-dihydro-1,3-dimethyl-2H-imidazol-2-ylidene)diiodopalladium; potassium carbonate; at 80 ℃; for 24h; Inert atmosphere;

DOI:10.14233/ajchem.2013.14863

upstream raw materials:

(1,1'-biphenyl)-4,4'-dicarbonitrile

(4-bromophenyl)(phenyl)methanone

4-iodobenzophenone

biphenyl

Downstream raw materials:

4,4'-Bis-(α-hydroxy-2-methyl-benzhydryl)-biphenyl

[1,1’-biphenyl]-4,4’-diylbis(diphenylmethanol)

4,4'-dibenzyldiphenyl

4,4'-bis<(1-naphthyl)phenylhydroxymethyl>biphenyl

Refernces

• 1、 Cho, Soo Kyung,Song, Ju Hyun,Hahn, Jung Tae,Jung, Dai Il. "Biaryl diketone synthesis via palladium-catalyzed carbonylative coupling with carbon monoxide or various metal carbonyls". . p. 1567 - 1570. Retrieved 2016/10/13.
• 2、 Lipshutz, Bruce H.,Moser, Ralph,Voigtritter, Karl R.. "Miyaura borylations of aryl bromides in water at room temperature". . p. 691 - 695. Retrieved 2013/01/09.