7-Bromo-1-methylnaphthalene

Base Information

• Chemical Name: 7-Bromo-1-methylnaphthalene
• CAS No.: 33295-35-1
• Molecular Formula: C11H9Br
• Molecular Weight: 221.09300
• DSSTox Substance ID: DTXSID60496162
• Nikkaji Number: J1.415.672K
• Wikidata: Q82344844
• Mol file: 33295-35-1.mol

Synonyms:7-Bromo-1-methylnaphthalene;33295-35-1;7-Bromo-1-methyl-naphthalene;2-Bromo-8-methylnaphthalene;SCHEMBL9485473;DTXSID60496162;AYHZOTAQXZRRIH-UHFFFAOYSA-N;MFCD17012268;AKOS024438899;AS-58983;CS-0153393;FT-0755570;EN300-207653;A875332

Chemical Property of 7-Bromo-1-methylnaphthalene

Chemical Property:

• PSA: 0.00000
• LogP: 3.91070
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 219.98876
• Heavy Atom Count: 12
• Complexity: 155

Purity/Quality:

98% ^*data from raw suppliers

7-Bromo-1-methyl-naphthalene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=C2C=C(C=CC2=CC=C1)Br

Technology Process of 7-Bromo-1-methylnaphthalene

There total 10 articles about 7-Bromo-1-methylnaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7-bromo-1-methyl-1,2,3,4-tetrahydronaphthalen-1-ol (35943-86-3) → 2-bromo-8-methylnaphthalene (33295-35-1)

Guidance literature:

With triphenylmethyl alcohol; trifluoroacetic acid; for 48h;

DOI:10.1021/ol061701p

Reference yield:

7-bromo-1-methyl-3,4-dihydronaphthalene (35943-87-4) → 2-bromo-8-methylnaphthalene (33295-35-1)

Guidance literature:

With tetrachloromethane; bromine; at -10 ℃; Erhitzen des Reaktionsprodukts auf 200grad;

DOI:10.1021/ja01268a051

Reference yield:

7-bromo-3,4-dihydro-2H-naphthalen-1-one (32281-97-3) → 2-bromo-8-methylnaphthalene (33295-35-1)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran / 3 h / cooling

2: 60 mg / TFA; triphenylmethanol / 48 h

With triphenylmethyl alcohol; trifluoroacetic acid; In tetrahydrofuran; 1: Grignard reaction;

DOI:10.1021/ol061701p

upstream raw materials:

7-bromo-1-methyl-3,4-dihydronaphthalene

methyl magnesium iodide

7-bromo-3,4-dihydro-2H-naphthalen-1-one

tetrachloromethane

Downstream raw materials:

C₃₃H₂₅NO₂

1-(1,2-Dibromethyl)-7-<2-(1,2-dibromethyl)phenyl>naphthalin

1-Brommethyl-7-<2-(brommethyl)phenyl>naphthalin

2-(8-Fluor-naphthoyl)-benzoesaeure

Refernces

• 1、 Singh, Ishwar,Seitz, Oliver. "Diastereoselective synthesis of β-aryl-C-nucleosides from 1,2-anhydrosugars". . p. 4319 - 4322. Retrieved 2007/10/03.