5-Chlorobenzo[b]phosphindole

Base Information

• Chemical Name: 5-Chlorobenzo[b]phosphindole
• CAS No.: 33300-85-5
• Molecular Formula: C12H8ClP
• Molecular Weight: 218.622
• Hs Code.: 2934999090
• Nikkaji Number: J876.092F
• Mol file: 33300-85-5.mol

Synonyms:5-chlorobenzo[b]phosphindole;5-CHLORO-5H-DIBENZOPHOSPHOLE;5-chlorodibenzophosphole;SCHEMBL7704265;ONQRFNKLTKSHEJ-UHFFFAOYSA-N

Chemical Property of 5-Chlorobenzo[b]phosphindole

Chemical Property:

• Melting Point: 146-179°C
• Boiling Point: 146-148 °C(Press: 5 Torr)
• PSA: 0.00000
• LogP: 4.98150
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 218.0052149
• Heavy Atom Count: 14
• Complexity: 196

Purity/Quality:

99% ^*data from raw suppliers

5-Chlorobenzo[b]phosphindole ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C3=CC=CC=C3P2Cl

Technology Process of 5-Chlorobenzo[b]phosphindole

There total 7 articles about 5-Chlorobenzo[b]phosphindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

biphenyl-2,2'-diyl-bis-lithium (16291-32-0) → 9-Chlorodibenzophosphole (33300-85-5)

Guidance literature:

With phosphorus trichloride; In tetrahydrofuran;

DOI:10.1080/10426509608037969

Reference yield:

2,2'-dibromobiphenyl (13029-09-9) → 9-Chlorodibenzophosphole (33300-85-5)

Guidance literature:

2,2'-dibromobiphenyl; With tert.-butyl lithium; In tetrahydrofuran; pentane; at -78 ℃; for 4h; Inert atmosphere;

With phosphorus trichloride; In tetrahydrofuran; pentane; at -198 - 20 ℃; Inert atmosphere;

DOI:10.1246/cl.2011.174

Reference yield:

2,2'-dibromobiphenyl (13029-09-9) → 5-bromo-5H-dibenzophosphole + 9-Chlorodibenzophosphole (33300-85-5)

Guidance literature:

2,2'-dibromobiphenyl; With n-butyllithium; In diethyl ether; hexane; at 0 - 25 ℃; for 1h; Inert atmosphere; Schlenk technique;

With phosphorus trichloride; In diethyl ether; hexane; at -198 - 25 ℃; for 0.25h; Inert atmosphere; Schlenk technique;

DOI:10.1039/c5dt02976g

upstream raw materials:

5-oxo-5H-5λ⁵-dibenzophosphol-5-ol

2-Phenylphen-1-oxydichlorphosphan

[1,1'-biphenyl]-2-diazonium tetrafluoroborate

biphenyl-2,2'-diyl-bis-lithium

Downstream raw materials:

5-(2,6-bis-tetrahydropyran-2-yloxymethyl-phenyl)-5H-benzo[b]phosphindole

9-phenyl-9-phosphafluorene

5-oxo-5H-5λ⁵-dibenzophosphol-5-ol

[2-(5-oxo-5H-5λ⁵-benzo[b]phosphindol-5-yl)-m-phenylene]-bis-methanol

Refernces

• 1、 Johnson, Stephen E.,Knobler, Carolyn B.. "Synthesis and structural characterization of a tetraaryldiphosphorus cation and a dialkylphosphonium salt". . p. 227 - 240. Retrieved 1996.
• 2、 -. "TETRAMERISATION OF ETHYLENE". Page/Page column 30. . Retrieved 2014/12/09.