Ethanone, 1-(3,6-dihydroxy-2-methoxyphenyl)-

Base Information

• Chemical Name: Ethanone, 1-(3,6-dihydroxy-2-methoxyphenyl)-
• CAS No.: 33539-20-7
• Molecular Formula: C9H10O4
• Molecular Weight: 182.176
• Hs Code.: 2914509090
• Mol file: 33539-20-7.mol

Synonyms:2,7-DIHYDROXY NAPHTHALENE-3,6-DISULPHONATE;3,6-dihydroxy-2-methoxyacetophenone;3,6-Dihydroxynaphthalene-2,7-Disulfonic Acid;6-methoxy-2,5-dihydroxyacetophenone;2,5-dihydroxy-6-methoxyacetophenone;3,6-Dihydroxy-naphthalin-2,7-disulfonsaeure;2,7-Naphthalenedisulfonic acid,3,6-dihydroxy;3,6-dihydroxy-2,7-naphthalenesulfonic acid;2-acetyl-3-methoxy-hydroquinone;2,4-dihydroxy-6-methoxy acetophenone;2,7-Dihydroxy-3,6-naphthalenedisulfonic acid;

Chemical Property of Ethanone, 1-(3,6-dihydroxy-2-methoxyphenyl)-

Chemical Property:

• Melting Point: 91°C
• PSA: 66.76000
• LogP: 1.30900

Purity/Quality:

1-(3,6-dihydroxy-2-methoxyphenyl)ethanone 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethanone, 1-(3,6-dihydroxy-2-methoxyphenyl)-

There total 7 articles about Ethanone, 1-(3,6-dihydroxy-2-methoxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

methanol (67-56-1) + 2,5-Dihydroxyacetophenone (490-78-8) → 6-methoxy-2,5-dihydroxyacetophenone (33539-20-7)

Guidance literature:

With calcium sulfate; copper(l) chloride; In ethyl acetate; acetonitrile; at 20 ℃; for 3h; Further Variations:; Reaction partners; Product distribution;

DOI:10.1016/S0040-4020(00)00947-9

Reference yield: 60.0%

2'-hydroxy-6'-methoxyacetophenone (703-23-1) → 6-methoxy-2,5-dihydroxyacetophenone (33539-20-7)

Guidance literature:

With sodium hydroxide; dipotassium peroxodisulfate; at 20 ℃; for 168h;

DOI:10.1021/jm060915+

Reference yield: 40.0%

2'-hydroxy-6'-methoxyacetophenone (703-23-1) → 6-methoxy-2,5-dihydroxyacetophenone (33539-20-7) + 1-(2,3-dihydroxy-6-methoxy-phenyl)-ethanone (56358-73-7)

Guidance literature:

2'-hydroxy-6'-methoxyacetophenone; With sodium hydroxide; dipotassium peroxodisulfate; In water; at 20 ℃;

With hydrogenchloride; sodium sulfite; In water; for 2h; Heating / reflux;

upstream raw materials:

2'-hydroxy-6'-methoxyacetophenone

methanol

2-Acetyl-1,4-benzoquinone

2,5-Dihydroxyacetophenone

Downstream raw materials:

1-[3-(3-chloro-benzyloxy)-6-hydroxy-2-methoxy-phenyl]-ethanone

6-(3-chloro-benzyloxy)-2-(4-iodo-benzyloxy)-5-methoxy-chromen-4-one

6-(3-chloro-benzyloxy)-2-(3-iodo-benzyloxy)-5-methoxy-chromen-4-one

6-(3-chloro-benzyloxy)-2-(3,5-dichlorobenzyloxy)-5-methoxy-chromen-4-one

Refernces

• 1、 -. "CHEMOTHERAPEUTIC FLAVONOIDS, AND SYNTHESES THEREOF". Page/Page column 26; 42-43. . Retrieved 2008/12/06.
• 2、 -. "FLAVONES". Page/Page column 17; 44; 46-47. . Retrieved 2008/06/13.