Cyclohexanone O-ethyl oxime

Base Information

• Chemical Name: Cyclohexanone O-ethyl oxime
• CAS No.: 3376-38-3
• Molecular Formula: C8H15NO
• Molecular Weight: 141.213
• Hs Code.: 2928000090
• Mol file: 3376-38-3.mol

Synonyms:cyclohexanon-(O-ethyl oxime );Cyclohexanonoxim-O-aethylaether;Cyclohexanon-(O-aethyl-oxim);Cyclohexanon-[O-ethyl-oxim];

Chemical Property of Cyclohexanone O-ethyl oxime

Chemical Property:

• PSA: 21.59000
• LogP: 2.34300

Purity/Quality:

99%, ^*data from raw suppliers

O-ETHYLCYCLOHEXANONE OXIME 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclohexanone O-ethyl oxime

There total 5 articles about Cyclohexanone O-ethyl oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

O-ethylhydroxylamine hydrochloride (3332-29-4) + cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) → cyclohexanone O-ethyl oxime (3376-38-3)

Guidance literature:

With sodium acetate; In ethanol; water; at 75 ℃; for 3h;

DOI:10.1021/acs.orglett.8b02738

Reference yield:

1-nitrocyclohexane (1122-60-7) → cyclohexanone-oxime (100-64-1) + cyclohexanone O-ethyl oxime (3376-38-3)

Guidance literature:

With diethyl sulfate;

Reference yield:

N-ethoxyphthalimide (1914-21-2) + cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) → cyclohexanone O-ethyl oxime (3376-38-3)

Guidance literature:

N-ethoxyphthalimide; With hydrazine hydrate; In methanol; at 0 ℃; for 0.5h;

cyclohexanone; With sodium acetate; In methanol; water; at 65 ℃; for 5h;

DOI:10.1039/c4cc05655h

upstream raw materials:

cyclohexanone-oxime

diethyl sulfate

1-nitrocyclohexane

N-hydroxyphthalimide

Downstream raw materials:

2-Bromcyclohexanonoxim-O-aethylaether

Refernces

• 1、 Kang, Taek,Kim, Heejeong,Kim, Jeung Gon,Chang, Sukbok. "Synthesis of 1,2-amino alcohols via catalytic C-H amidation of sp3 methyl C-H bonds". . p. 12073 - 12075. Retrieved 2014/12/11.