2-Octylpyridine

Base Information

• Chemical Name: 2-Octylpyridine
• CAS No.: 33841-61-1
• Molecular Formula: C13H21N
• Molecular Weight: 191.316
• Mol file: 33841-61-1.mol

Synonyms:Pyridine,2-octyl;2-Octyl-pyridin;2-octyl-pyridine;2-n-octylpyridine;

Chemical Property of 2-Octylpyridine

Chemical Property:

• PSA: 12.89000
• LogP: 3.98460
• Storage Temp.: 2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

2-Octylpyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-Octylpyridine (cas# 33841-61-1) is useful as taste modifying product for flavored foods (1). Also, intermediate for pyridinium ionic liquids (2).

Technology Process of 2-Octylpyridine

There total 2 articles about 2-Octylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

2-chloropyridine (109-09-1) + 1-bromo-octane (111-83-1) → 2-n-octylpyridine (33841-61-1) + Hexadecane (544-76-3)

Guidance literature:

1-bromo-octane; With nickel(II) bromide trihydrate; bathophenanthroline; In N,N-dimethyl-formamide; at 40 ℃; for 0.333333h;

2-chloropyridine; With manganese; In N,N-dimethyl-formamide; at 40 ℃; Sealed tube;

DOI:10.1055/s-0033-1340151

Reference yield: 52.0%

2-bromo-pyridine (109-04-6) + n-octylboronic acid (28741-08-4) → 2-n-octylpyridine (33841-61-1)

Guidance literature:

With potassium carbonate; bis(η3-allyl-μ-chloropalladium(II)); (1RS,2RS,3SR,4SR)-1,2,3,4-tetrakis((diphenylphosphanyl)methyl)cyclopentane; In xylene; at 130 ℃; for 20h;

DOI:10.1016/j.tet.2004.03.009

Reference yield:

2-n-octylpyridine (33841-61-1) + methyl p-toluene sulfonate (80-48-8) → 1-methyl-2-octyl-pyridinium; toluene-4-sulfonate

Guidance literature:

upstream raw materials:

2-bromo-pyridine

n-octylboronic acid

2-chloropyridine

1-bromo-octane

Refernces

• 1、 Kondolff, Isabelle,Doucet, Henri,Santelli, Maurice. "Tetraphosphine/palladium catalysed Suzuki cross-coupling reactions of aryl halides with alkylboronic acids". . p. 3813 - 3818. Retrieved 2007/10/03.