3-Hydroxy-alpha-methyl-DL-tyrosine

Base Information Edit

Chemical Name:3-Hydroxy-alpha-methyl-DL-tyrosine
CAS No.:55-40-3
Deprecated CAS:555-29-3
Molecular Formula:C10H13 N O4
Molecular Weight:211.218
Hs Code.:2916399090
European Community (EC) Number:209-088-7,200-232-4
NSC Number:169916
UNII:33TD13T99R
DSSTox Substance ID:DTXSID60970356
Nikkaji Number:J1.682.491G
Wikidata:Q27256299
ChEMBL ID:CHEMBL718
Mol file:55-40-3.mol

Synonyms:3-Hydroxy-alpha-methyl-DL-tyrosine;55-40-3;DL-Methyldopa;555-29-3;3-Hydroxy-alpha-methyltyrosine;Mulfasin;2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid;Metholes;DL-alpha-Methyl DOPA;(+/-)-methyldopa;racemic alpha-Methyldopa;(+-)-alpha-Methyldopa;.alpha.-Methyl dopa;Methyldopa (Racemic);Methyldopa anhydrous, (+/-)-;L-(.alpha.-Md);(-)-Methyldopa;Dl-.alpha.-methyl dopa;.alpha.-Methyldopa, L-;EINECS 209-088-7;Racemic .alpha.-methyldopa;Medopa;UNII-33TD13T99R;33TD13T99R;EINECS 200-232-4;(+/-)-3-(3,4-dihydroxyphenyl)-2-methyl-DL-alanine;DL-Tyrosine, 3-hydroxy-alpha-methyl-;L-.alpha.-Methyldopa;.alpha.-Methyl-L-dopa;.alpha.-Methyl-L-(3,4-dihydroxyphenyl)alanine;L-.alpha.-Methyl-(3,4-dihydroxyphenyl)alanine;(S)-(-)-.alpha.-Methyldopa;.alpha.-Methyl-.beta.-(3,4-dihydroxyphenyl)-L-alanine;ALANINE, 3-(3,4-DIHYDROXYPHENYL)-2-METHYL-, DL-;L-(-)-.alpha.-Methyl-.beta.-(3,4-dihydroxyphenyl)alanine;2-Methyl-3-(3,4-dihydroxyphenyl)alanine;rac Alpha-Methyl DOPA;SR-01000075631;Elanpres;Equibar;Methyl-dopa;Tyrosine, 3-hydroxy-.alpha.-methyl-;.alpha.-Medopa;3,4-Dihydroxy-2-methylphenylalanine #;Methyldopa dl-form;Tyrosine, 3-hydroxy-alpha-methyl-;.alpha.-Methyldopa;.alpha.-Methyl-L-3,4-dihydroxyphenylalanine;D-?-Methyl DOPA;rac ?-Methyl DOPA;DL-alpha-Methyl-DOPA;rac alpha -Methyl DOPA;Alanine, 3-(3,4-dihydroxyphenyl)-2-methyl-, L-;CHEMBL718;Lopac0_000770;3-hydroxy-alpha-methyltyrosin;SCHEMBL196981;WLN: QVXZ1&1R CQ DQ;METHYLDOPA DL-FORM [MI];DTXSID60970356;CHEBI:180994;HMS3259C21;HMS3262I22;HMS3266O08;2,2,3,4,4-PENTABDE;BCP28393;Tox21_500770;(+/-)-.ALPHA.-METHYLDOPA;AKOS003273681;AKOS017258656;AC-8433;CCG-204855;LP00770;NC00520;SDCCGSBI-0050748.P005;NCGC00015631-03;NCGC00015631-04;NCGC00015631-05;NCGC00015631-09;NCGC00094109-01;NCGC00094109-02;NCGC00261455-01;AC-11788;LS-16067;SBI-0050748.P004;Alanine,4-dihydroxyphenyl)-2-methyl-, L-;alpha-methyl-3,4-dihydroxy-dl-phenylalanine;EU-0100770;FT-0603468;FT-0604487;FT-0671717;FT-0671718;( inverted exclamation markA)-ALPHA-Methyldopa;2-(3,4-dihydroxybenzyl)-2-aminopropanoic acid;3-(3,4-dihydroxyphenyl)-2-methyl-DL-alanine;EN300-297472;M 7277;M-3586;Alanine,4-dihydroxyphenyl)-2-methyl-, L-(-)-;alpha-Methyl-DL-beta-3,4-Dihydroxyphenylalanine;A830691;L001029;SR-01000076007;(?)-3-(3,4-dihydroxyphenyl)-2-methyl-DL-alanine;(y)-3-(3,4-dihydroxyphenyl)-2-methyl-DL-alanine;DL-2-METHYL-3-(3,4-DIHYDROXYPHENYL)ALANINE;SR-01000075631-1;SR-01000075631-3;SR-01000076007-1;W-105556;METHYLN-4-BOC-N-1-CBZ-2-PIPERAZINECARBOXYLATE;Q27256299;2-amino-2-methyl-3-(3,4-dihydroxyphenyl)propionic acid;2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoicacid;DL-.ALPHA.-METHYL-3-(3,4-DIHYDROXYPHENYL)ALANINE;L(-)-.beta.-(3,4-Dihydroxyphenyl)-.alpha.-methylalanine;L-(-)-.beta.-(3,4-Dihydroxyphenyl)-.alpha.-methylalanine;( inverted question mark)-3-(3,4-dihydroxyphenyl)-2-methyl-DL-alanine;2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-2- METHYL-PROPIONIC ACID(CATECHOL METABOLITE)

Suppliers and Price of 3-Hydroxy-alpha-methyl-DL-tyrosine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
racα-MethylDOPA
2.5mg
$ 110.00

Medical Isotopes, Inc.
racα-MethylDOPA
2.5 mg
$ 860.00

American Custom Chemicals Corporation
DL-METHYLDOPA SESQUIHYDRATE 95.00%
5MG
$ 500.92

Acrotein
2-Methyl-3-(3,4-dihydroxyphenyl)-DL-alanine 97%
100g
$ 70.58

Total 43 raw suppliers

Chemical Property of 3-Hydroxy-alpha-methyl-DL-tyrosine Edit

Chemical Property:

Melting Point:300-301 °C (decomp)
Boiling Point:441.6°Cat760mmHg
PKA:2.28±0.26(Predicted)
Flash Point:220.9°C
PSA：103.78000
Density:1.403g/cm³
LogP:1.14260
Storage Temp.:−20°C
Solubility.:DMSO (Slightly), Water (Slightly)
XLogP3:-1.9
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:211.08445790
Heavy Atom Count:15
Complexity:246

Purity/Quality:

99%, ^*data from raw suppliers

racα-MethylDOPA ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36
Safety Statements: 26-36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CC1=CC(=C(C=C1)O)O)(C(=O)O)N

Technology Process of 3-Hydroxy-alpha-methyl-DL-tyrosine

There total 8 articles about 3-Hydroxy-alpha-methyl-DL-tyrosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 55-40-3,555-29-3,88620-56-8
alpha-methyldopa

Guidance literature:: With hydrogen bromide;
DOI:10.1021/ja01608a046

Reference yield:

: 55-40-3,555-29-3,88620-56-8
alpha-methyldopa

Guidance literature:: With hydrogenchloride;
DOI:10.1021/ja01608a046

Reference yield:

: 84713-76-8
2-Amino-3-(3,4-bis-benzyloxy-phenyl)-2-methyl-propionic acid ethyl ester; hydrochloride

: 55-40-3,555-29-3,88620-56-8
alpha-methyldopa

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; Yield given. Multistep reaction; 1.) ethanol;
DOI:10.1016/S0040-4039(00)88719-5