Cyclopentanone, 2,5-bis(phenylmethylene)-, (E,E)-

Base Information

• Chemical Name: Cyclopentanone, 2,5-bis(phenylmethylene)-, (E,E)-
• CAS No.: 34611-43-3
• Molecular Formula: C19H16O
• Molecular Weight: 260.335
• Mol file: 34611-43-3.mol

Synonyms:2,5-(E,E)-bis(benzylidene)cyclopentanone;2,5-bis[(E)-phenylmethylidene]cyclopentanone;(E,E)-2,5-dibenzylidenecyclopentanone;α,α'-dibenzylidene cyclopentanone;(2E,5E)-2,5-dibenzylidenecyclopentanone;α,α'-bis(benzylidene)cyclopentanone;2,5-Bis-[1-phenyl-meth-(E)-ylidene]-cyclopentanone;

Chemical Property of Cyclopentanone, 2,5-bis(phenylmethylene)-, (E,E)-

Chemical Property:

• PSA: 17.07000
• LogP: 4.51650

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclopentanone, 2,5-bis(phenylmethylene)-, (E,E)-

There total 8 articles about Cyclopentanone, 2,5-bis(phenylmethylene)-, (E,E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

benzaldehyde (100-52-7) + cyclopentanone (120-92-3) → 2,5-dibenzylidene cyclopentanone (34611-43-3)

Guidance literature:

With PEG₄₀₀; sodium hydroxide; In water; at 20 ℃; for 0.5h;

DOI:10.1246/cl.2005.576

Reference yield: 80.0%

1,1-diethoxy-cyclopentane (23786-93-8) + benzaldehyde (100-52-7) → 2,5-dibenzylidene cyclopentanone (34611-43-3)

Guidance literature:

With boron trifluoride diethyl etherate; for 0.166667h; microwave irradiation;

Reference yield: 69.0%

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + benzaldehyde (100-52-7) → 2,5-dibenzylidene cyclopentanone (34611-43-3)

Guidance literature:

With bis(cyclopentadienyl)dihydrozirconium; nickel dichloride; at 130 ℃; for 10h;

DOI:10.1021/jo00387a025

upstream raw materials:

cyclohexanone

benzaldehyde

cyclopentanone

1,1-diethoxy-cyclopentane

Downstream raw materials:

(E)-2-benzyl-5-benzylidenecyclopentanone

2-amino-7-benzylidene-4,5,6,7-tetrahydro-4-phenylcyclopentapyran-3-carbonitrile

Refernces

• 1、 Batalin, Sergey,Golikova, Margarita,Khrustaleva, Alexandra,Pchelintseva, Nina. "PEG-400 assisted Kr?hnke synthesis of 2-(2-hydroxyphenyl)-4-arylpyridines annulated by C5-C6 cycles with substituted benzylidene group". . p. 659 - 668. Retrieved 2020.
• 2、 Tanemura, Kiyoshi,Rohand, Taoufik. "Activated charcoal-mediated synthesis of chalcones catalyzed by NaOH in water". . . Retrieved 2021/02/27.