Methyl 4-aMino-3,6-dichloropicolinate

Base Information

• Chemical Name: Methyl 4-aMino-3,6-dichloropicolinate
• CAS No.: 350601-39-7
• Molecular Formula: C7H6Cl2N2O2
• Molecular Weight: 221.043
• Mol file: 350601-39-7.mol

Synonyms:

Chemical Property of Methyl 4-aMino-3,6-dichloropicolinate

Chemical Property:

• Boiling Point: 400.8±40.0 °C(Predicted)
• PKA: -0.96±0.10(Predicted)
• Density: 1.506±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Solubility.: Dichloromethane

Purity/Quality:

99% ^*data from raw suppliers

Methyl4-Amino-3,6-dichloropyridine-2-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Methyl 4-Amino-3,6-dichloropyridine-2-carboxylate is an intermediate in the synthesis of Arylex (A794890), which exhibits potent dicot weed control; Herbicide.

Technology Process of Methyl 4-aMino-3,6-dichloropicolinate

There total 2 articles about Methyl 4-aMino-3,6-dichloropicolinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.26%

methanol (67-56-1) + aminopyralid (150114-71-9) → methyl 4-amino-3,6-dichloropyridine-2-carboxylate (350601-39-7)

Guidance literature:

With thionyl chloride; at -5 - 60 ℃; for 7h; Reagent/catalyst;

Reference yield:

→ methyl 4-amino-3,6-dichloropyridine-2-carboxylate (350601-39-7) + ethyl 4-amino-3,6-dichloropyridine-2-carboxylate (350601-41-1)

Guidance literature:

Reference yield: 91.0%

methyl 4-amino-3,6-dichloropyridine-2-carboxylate (350601-39-7) → 4-amino-3,6-dichloro-5-bromopyridine-2-carboxylic acid

Guidance literature:

With bromine; In sulfuric acid;

upstream raw materials:

methanol

aminopyralid

Downstream raw materials:

methyl 4-amino-3-chloro-6-(3,4-dimethylphenyl)pyridine-2-carboxylate

4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methylthio-phenyl)pyridine-2-carboxylic acid methyl ester

Refernces

• 1、 -. "Compound containing fluorochloropyridine oxime ester structure, preparation method and application thereof and herbicide". Paragraph 0060-0062. . Retrieved 2019/04/06.
• 2、 -. "4-aminopicolinates and their use as herbicides". . . Retrieved 2008/06/13.