1,4-Bis(bromomethyl)cyclohexane

Base Information

• Chemical Name: 1,4-Bis(bromomethyl)cyclohexane
• CAS No.: 35541-75-4
• Molecular Formula: C8H14Br2
• Molecular Weight: 270.007
• Hs Code.: 2903890090
• European Community (EC) Number: 621-785-1
• DSSTox Substance ID: DTXSID00394214
• Mol file: 35541-75-4.mol

Synonyms:1,4-bis(bromomethyl)cyclohexane;35541-75-4;1,4-Bis-bromomethyl-cyclohexane;TRANS-1,4-BIS(BROMOMETHYL)CYCLOHEXANE;57702-84-8;C8H14Br2;1,4-bis-(bromomethyl)cyclohexane;SCHEMBL246935;SCHEMBL7231300;SCHEMBL21481657;1,4-dibromo-1-methylcyclohexane;DTXSID00394214;MYALOPJJAPLQSJ-UHFFFAOYSA-N;MFCD00153994;AKOS024258335;AT36024;AT36025;AT36026;SB36800;AS-10707;(1r,4r)-1,4-bis(bromomethyl)cyclohexane;CIS-1,4-BIS(BROMOMETHYL)CYCLOHEXANE;CS-0320230;FT-0714455;EN300-39870541;15898-77-8

Chemical Property of 1,4-Bis(bromomethyl)cyclohexane

Chemical Property:

• PSA: 0.00000
• LogP: 3.58260
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 269.94418
• Heavy Atom Count: 10
• Complexity: 73.3

Purity/Quality:

99%, ^*data from raw suppliers

1,4-Bis-bromomethyl-cyclohexane 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1CC(CCC1CBr)CBr

Technology Process of 1,4-Bis(bromomethyl)cyclohexane

There total 1 articles about 1,4-Bis(bromomethyl)cyclohexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

bis-1,4-(hydroxymethyl)cyclohexane (105-08-8) → 1,4-bis-(bromomethyl)cyclohexane (35541-75-4)

Guidance literature:

With phosphorus tribromide; In benzene; for 1.25h; Heating;

DOI:10.1021/jo00129a028

Reference yield: 56.0%

2-phenyl-indole (948-65-2) + 1,4-bis-(bromomethyl)cyclohexane (35541-75-4) → C36H34N2

Guidance literature:

2-phenyl-indole; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h; Inert atmosphere;

1,4-bis-(bromomethyl)cyclohexane; In N,N-dimethyl-formamide; at 20 ℃; for 3.5h; Inert atmosphere;

Reference yield: 30.0%

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone (22246-18-0) + 1,4-bis-(bromomethyl)cyclohexane (35541-75-4) → 7-((4-(bromomethyl)cyclohexyl)methoxy)-3,4-dihydroquinolin-2(1H)-one (1354030-56-0)

Guidance literature:

With potassium carbonate; In ethanol; Reflux;

upstream raw materials:

bis-1,4-(hydroxymethyl)cyclohexane

Downstream raw materials:

1,4-dimethylidenecyclohexane

4'-(4-bromomethyl-cyclohexylmethylsulfanyl)-4,5-bis-(2-ethyl-butylsulfanyl)-[2,2']bi[[1,3]dithiolylidene]

(E)-4-[3,5-Bis-(3,5-bis-benzyloxy-benzyloxy)-benzylsulfanyl]-4'-(4-bromomethyl-cyclohexylmethylsulfanyl)-[2,2']bi[[1,3]dithiolylidene]

7-((4-(bromomethyl)cyclohexyl)methoxy)-3,4-dihydroquinolin-2(1H)-one

Refernces