Perfluoro-5-(pentafluoroethyl)oxolane

Base Information

• Chemical Name: Perfluoro-5-(pentafluoroethyl)oxolane
• CAS No.: 356-48-9
• Molecular Formula: C6F12O
• Molecular Weight: 316.046
• DSSTox Substance ID: DTXSID30870516
• Nikkaji Number: J27.271J
• Mol file: 356-48-9.mol

Synonyms:Perfluoro-5-(pentafluoroethyl)oxolane;SCHEMBL1359047;DTXSID30870516;AJYRBQGTPUSTHS-UHFFFAOYSA-N;356-48-9;NS00019371

Chemical Property of Perfluoro-5-(pentafluoroethyl)oxolane

Chemical Property:

• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 13
• Rotatable Bond Count: 1
• Exact Mass: 315.9757526
• Heavy Atom Count: 19
• Complexity: 382

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1(C(C(OC1(C(C(F)(F)F)(F)F)F)(F)F)(F)F)(F)F

Technology Process of Perfluoro-5-(pentafluoroethyl)oxolane

There total 3 articles about Perfluoro-5-(pentafluoroethyl)oxolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.2%

7-oxabicyclo(2.2.1)heptane (279-49-2) → perfluoropentane (678-26-2) + perfluorohexanoyl fluoride (355-38-4) + perfluoro(2-ethyltetrahydrofuran) (356-48-9)

Guidance literature:

With fluorine; at -120 - 20 ℃; for 336h; Yields of byproduct given;

DOI:10.1021/jo00236a016

Reference yield:

oxane-2-yl-methyl acetate (5440-83-5,116779-14-7) → perfluoro(2-methyl-1,3,5-trioxaspiro[4.5]decane) (874634-51-2) + perfluorooxane (355-79-3) + perfluoro(2-methyloxane) (356-47-8) + perfluoro(2-ethyltetrahydrofuran) (356-48-9)

Guidance literature:

With hydrogen fluoride; at 7 - 8 ℃; for 5.95h; Further byproducts given; Electrochemical reaction;

DOI:10.1016/j.jfluchem.2004.11.014

Reference yield:

oxane-2-yl-methyl acetate (5440-83-5,116779-14-7) → perfluoro(oxane-2-ylcarbonylfluoride) + perfluoro(2-methyl-1,3,5-trioxaspiro[4.5]decane) (874634-51-2) + perfluoro(2-methyloxane) (356-47-8) + perfluoro(2-ethyltetrahydrofuran) (356-48-9)

Guidance literature:

With hydrogen fluoride; at 7 - 8 ℃; for 5.81667h; Further byproducts given; Electrochemical reaction;

DOI:10.1016/j.jfluchem.2004.11.014

upstream raw materials:

7-oxabicyclo(2.2.1)heptane

oxane-2-yl-methyl acetate

Refernces

• 1、 Huang, Hsu-Nan,Persico, Daniel F.,Lagow, Richard J.,Clark, Leland C.. "Synthesis of Unusual Perfluorocarbon Ethers and Amines Containing Bulky Fluorocarbon Groups: New Biomedical Materials". . p. 78 - 85. Retrieved 2007/10/02.