Benzene, 1-chloro-2-(1-methylethenyl)-

Base Information

• Chemical Name: Benzene, 1-chloro-2-(1-methylethenyl)-
• CAS No.: 3609-45-8
• Molecular Formula: C9H9Cl
• Molecular Weight: 152.623
• Mol file: 3609-45-8.mol

Synonyms:

Chemical Property of Benzene, 1-chloro-2-(1-methylethenyl)-

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzene, 1-chloro-2-(1-methylethenyl)-

There total 12 articles about Benzene, 1-chloro-2-(1-methylethenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

methyl magnesium iodide (917-64-6) + methyl chlorobenzoate (610-96-8) → 1-chloro-2-(prop-1-en-2-yl)benzene (3609-45-8)

Guidance literature:

methyl magnesium iodide; methyl chlorobenzoate; In diethyl ether; at 20 ℃;

With sulfuric acid; In acetic acid; for 2h; Further stages.;

DOI:10.1055/s-2007-984900

Reference yield: 81.0%

1-(2-chlorophenyl)ethanone (2142-68-9) + Methyltriphenylphosphonium bromide (1779-49-3) → 1-chloro-2-(prop-1-en-2-yl)benzene (3609-45-8)

Guidance literature:

Methyltriphenylphosphonium bromide; With potassium tert-butylate; In tetrahydrofuran; at 0 ℃; for 0.75h;

1-(2-chlorophenyl)ethanone; In tetrahydrofuran; at 0 - 20 ℃; for 16h;

DOI:10.1021/acs.orglett.8b02450

Reference yield: 79.0%

2-(2-chlorophenyl)propan-2-ol (3670-15-3) → 1-chloro-2-(prop-1-en-2-yl)benzene (3609-45-8)

Guidance literature:

With phthalic anhydride; at 125 - 130 ℃; for 24h;

DOI:10.1134/S1070428016060075

upstream raw materials:

2-(2-chlorophenyl)propan-2-ol

acetic anhydride

1-(2-chlorophenyl)ethanone

diazomethyl-trimethyl-silane

Downstream raw materials:

2-(1-methylethenyl)benzaldehyde

C₁₀H₉Br₂Cl

(2-isopropylphenyl)methanol

o-1-menthene

Refernces

• 1、 Guo, Pan,Sun, Wangbin,Liu, Yu,Li, Yong-Xin,Loh, Teck-Peng,Jiang, Yaojia. "Stereoselective Synthesis of Vinylcyclopropa[ b]indolines via a Rh-Migration Strategy". supporting information. p. 5978 - 5983. Retrieved 2020/08/05.
• 2、 Huang, Jingjia,Hu, Gang,An, Shaoyu,Chen, Dongding,Li, Minglei,Li, Pingfan. "Synthesis of N-Alkylpyridin-4-ones and Thiazolo[3,2- a]pyridin-5-ones through Pummerer-Type Reactions". . p. 9758 - 9769. Retrieved 2019/08/08.