Estra-1,3,5(10),7-tetraen-17-one, 3-(sulfooxy)-, sodium salt

Base Information

• Chemical Name: Estra-1,3,5(10),7-tetraen-17-one, 3-(sulfooxy)-, sodium salt
• CAS No.: 16680-47-0
• Molecular Formula: C18H20 O5 S . Na
• Molecular Weight: 370.402
• Mol file: 16680-47-0.mol

Synonyms:Equilin,sulfate, sodium salt (6CI); Estra-1,3,5(10),7-tetraen-17-one, 3-(sulfooxy)-, sodiumsalt (9CI); Estra-1,3,5(10),7-tetraen-17-one, 3-hydroxy-, hydrogen sulfate,sodium salt (8CI); Equilin sodium sulfate; Sodium equilin 3-monosulfate; Sodiumequilin sulfate

Chemical Property of Estra-1,3,5(10),7-tetraen-17-one, 3-(sulfooxy)-, sodium salt

Chemical Property:

• Melting Point: 159-161°C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 91.88000
• Density: g/cm³
• LogP: 3.95170
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Solubility.: Methanol, Water

Purity/Quality:

99%, ^*data from raw suppliers

Equilin3-SulfateSodiumSalt(StabilizedwithTRIS,50%w/w) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A metabolite of Equilin (E592800). Equilin 3-Sulfate Sodium Salt, is a metabolite of Equilin (E592800).

Technology Process of Estra-1,3,5(10),7-tetraen-17-one, 3-(sulfooxy)-, sodium salt

There total 3 articles about Estra-1,3,5(10),7-tetraen-17-one, 3-(sulfooxy)-, sodium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phenolic-depleted MUM → estrone/equilin depleted MUM + estrone sulfate sodium salt (438-67-5) + equilin sulfate sodium salt (16680-47-0)

Guidance literature:

With PS-DVB based resin with sulfate groups (weak cationic exchanger); Purification / work up;

Reference yield:

equilin (474-86-2) → equilin sulfate sodium salt (16680-47-0)

Guidance literature:

With pyridine; chlorosulphuric acid; chloroform; Durch Behandeln des Reaktionsprodukts mit methanol NaOH;

DOI:10.1021/ja01174a514

Reference yield:

equilin (474-86-2) → equilin sulfate sodium salt (16680-47-0)

Guidance literature:

With sodium hydroxide;

upstream raw materials:

equilin

Refernces