Penicillins

Base Information

• Chemical Name: Penicillins
• CAS No.: 575-54-2
• Molecular Formula: C14H19ClN2O4S2
• Molecular Weight: 378.89466
• Mol file: 575-54-2.mol

Synonyms:(2S,5R,6R)-6-[2-((Z)-3-Chloro-but-2-enylsulfanyl)-acetylamino]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid;6β-[2-(3-Chlor-but-2ξ-enylmercapto)-acetylamino]-penicillansaeure;

Chemical Property of Penicillins

Chemical Property:

• PSA: 137.31000
• LogP: 1.82270

Purity/Quality:

PENICILLIN S 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: The original fermentation derived penicillins were produced by growth of the fungus Penicillium chrysogenum on complex solid media, with the result that they were mixtures differing from one another in the identity of the side-chain moiety. When a sufficient supply of phenylacetic acid is present in liquid media, this is preferentially incorporated into the molecule to produce mainly benzylpenicillin (penicillin G in the old nomenclature). Use of phenoxyacetic acid instead leads to phenoxymethyl penicillin (penicillin V). More than two dozen different penicillins have been made in this way, but these two are the only ones that remain in clinical use. The bicyclic penicillin nucleus itself is prepared biosynthetically via a complex process from an acylated cysteinyl valyl peptide.

Technology Process of Penicillins

There total 1 articles about Penicillins which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 6β-[2-(3-chloro-but-2ξ-enylmercapto)-acetylamino]-penicillanic acid (575-54-2)

Guidance literature:

/BRN= 44307/;