Azetidine, 3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-(diphenylmethyl)-

Base Information

• Chemical Name: Azetidine, 3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-(diphenylmethyl)-
• CAS No.: 365997-70-2
• Molecular Formula: C32H35NOSi
• Molecular Weight: 477.721
• Mol file: 365997-70-2.mol

Synonyms:

Chemical Property of Azetidine, 3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-(diphenylmethyl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Azetidine, 3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-(diphenylmethyl)-

There total 2 articles about Azetidine, 3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-(diphenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(diphenylmethyl)-3-hydroxyazetidine (18621-17-5) + tert-butylchlorodiphenylsilane (58479-61-1) → 1-benzhydryl-3-(tert-butyl-diphenyl-silanyloxy)-azetidine (365997-70-2)

Guidance literature:

With 1H-imidazole; In DMF (N,N-dimethyl-formamide); at 0 - 20 ℃;

Reference yield:

1-(diphenylmethyl)-3-azetidinol hydrochloride (90604-02-7) → 1-benzhydryl-3-(tert-butyl-diphenyl-silanyloxy)-azetidine (365997-70-2)

Guidance literature:

Reference yield:

1-benzhydryl-3-(tert-butyl-diphenyl-silanyloxy)-azetidine (365997-70-2) → 3-(tert-butyl-diphenyl-silanyloxy)-azetidine

Guidance literature:

1-benzhydryl-3-(tert-butyl-diphenyl-silanyloxy)-azetidine; With carbonochloridic acid 1-chloro-ethyl ester; In 1,2-dichloro-ethane; at 20 - 80 ℃; for 2h;

With methanol; for 1h; Heating / reflux;

With hydrogenchloride; water; sodium hydrogencarbonate; more than 3 stages;

upstream raw materials:

1-(diphenylmethyl)-3-hydroxyazetidine

tert-butylchlorodiphenylsilane

1-(diphenylmethyl)-3-azetidinol hydrochloride

Refernces

• 1、 -. "ETHYLENEDIAMINE DERIVATIVES". . . Retrieved 2008/06/13.