Technology Process of 2-(2-Phenylethyl)benzoyl chloride
There total 10 articles about 2-(2-Phenylethyl)benzoyl chloride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: H2 / 5percent Pd/C / ethanol; ethyl acetate / 0.67 h / 20 °C / 1875.19 Torr
2: aq. NaOH / methanol / 15 h / 20 °C
3: oxalyl chloride; DMF / CH2Cl2 / 1 h / 20 °C
With
sodium hydroxide; oxalyl dichloride; hydrogen; N,N-dimethyl-formamide;
5percent Pd/C;
In
methanol; ethanol; dichloromethane; ethyl acetate;
DOI:10.1021/jm0002073
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: KOt-Bu / tetrahydrofuran / 1 h / 80 °C
1.2: tetrahydrofuran / 0.5 h / 80 °C
2.1: H2 / 5percent Pd/C / ethanol; ethyl acetate / 0.67 h / 20 °C / 1875.19 Torr
3.1: aq. NaOH / methanol / 15 h / 20 °C
4.1: oxalyl chloride; DMF / CH2Cl2 / 1 h / 20 °C
With
sodium hydroxide; oxalyl dichloride; potassium tert-butylate; hydrogen; N,N-dimethyl-formamide;
5percent Pd/C;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; ethyl acetate;
DOI:10.1021/jm0002073
