phenyl cyclohexanepropionate

Base Information

• Chemical Name: phenyl cyclohexanepropionate
• CAS No.: 94157-86-5
• Molecular Formula: C15H20 O2
• Molecular Weight: 232.323
• Hs Code.: 2916209090
• Mol file: 94157-86-5.mol

Synonyms:Cyclohexanepropionicacid, phenyl ester (6CI); Phenyl 3-cyclohexylpropanoate

Chemical Property of phenyl cyclohexanepropionate

Chemical Property:

• Vapor Pressure: 1.97E-06mmHg at 25°C
• Boiling Point: 379.4°C at 760 mmHg
• Flash Point: 276.3°C
• PSA: 26.30000
• Density: 1.027±0.06 g/cm3(Predicted)
• LogP: 3.95250

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of phenyl cyclohexanepropionate

There total 13 articles about phenyl cyclohexanepropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

cyclohexane (110-82-7,25012-93-5) + phenyl acrylate (937-41-7) → 3-Cyclohexylpropionsaeure-phenylester (94157-86-5)

Guidance literature:

With iron(III) chloride hexahydrate; In acetonitrile; at 25 ℃; for 15h; Inert atmosphere; UV-irradiation;

DOI:10.1039/d1gc01563j

Reference yield: 91.0%

phenyl acrylate (937-41-7) + 1,3-dioxoisoindolin-2-yl cyclohexanecarboxylate (126812-30-4) → 3-Cyclohexylpropionsaeure-phenylester (94157-86-5)

Guidance literature:

With diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; In N,N-dimethyl acetamide; at 25 ℃; for 12h; Solvent; Reagent/catalyst; Schlenk technique; Inert atmosphere; Irradiation;

Reference yield: 84.0%

Cyclohexyl iodide (626-62-0) + phenyl acrylate (937-41-7) → 3-Cyclohexylpropionsaeure-phenylester (94157-86-5)

Guidance literature:

With dimanganese decacarbonyl; diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; In dimethyl sulfoxide; at 20 ℃; for 24h; Inert atmosphere; Sealed tube; Irradiation;

DOI:10.1039/c9cc06400a

upstream raw materials:

3-cyclohexylpropionyl chloride

phenol

cyclohexane

Cyclohexane-d12

Downstream raw materials:

3-cyclohexyl-1-(4-hydroxy-phenyl)-propan-1-one

3-cyclohexyl-1-(2-hydroxyphenyl)propan-1-one

Refernces

• 1、 Ai, Han-Jun,Li, Chong-Liang,Wang, Hai,Wu, Xiao-Feng. "Rhodium-Catalyzed Carbonylative Coupling of Alkyl Halides with Phenols under Low CO Pressure". . p. 5147 - 5152. Retrieved 2020/05/27.
• 2、 -. "Catalyst-free alkyl carboxylate decarboxylation and decarboxylation Giese radical addition reaction". Paragraph 0068-0102. . Retrieved 2019/11/20.