Technology Process of Thiomorpholine, 4-(2,6-difluoro-4-nitrophenyl)-
There total 1 articles about Thiomorpholine, 4-(2,6-difluoro-4-nitrophenyl)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
N-ethyl-N,N-diisopropylamine;
In
acetonitrile;
at 0 - 20 ℃;
for 24h;
- Guidance literature:
-
With
hydrogen;
nickel;
In
tetrahydrofuran; water;
for 24h;
under 2068.65 Torr;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: iron; ammonium chloride / water; ethanol / 3 h / 70 °C
2.1: sodium hydrogencarbonate; acetone / water / 3 h / 0 - 20 °C
3.1: lithium tert-butoxide / methanol; tetrahydrofuran / 1 h / 0 °C
3.2: 16 h / 20 °C
4.1: oxone||potassium monopersulfate triple salt / water; methanol / 4 h / 0 - 20 °C
With
oxone||potassium monopersulfate triple salt; iron; sodium hydrogencarbonate; ammonium chloride; acetone; lithium tert-butoxide;
In
tetrahydrofuran; methanol; ethanol; water;
