3-Azidoanisole

Base Information

• Chemical Name: 3-Azidoanisole
• CAS No.: 3866-16-8
• Molecular Formula: C7H7N3O
• Molecular Weight: 149.152
• Hs Code.: 2929909090
• Mol file: 3866-16-8.mol

Synonyms:1-Azido-3-methoxybenzene;

Chemical Property of 3-Azidoanisole

Chemical Property:

• Flash Point: -33°C
• PSA: 58.98000
• LogP: 2.08976
• Storage Temp.: ?20°C

Purity/Quality:

95% ^*data from raw suppliers

1-Azido-3-methoxybenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s): 2090296
• Hazard Codes: F,T
• Statements: 11-38-48/23/24/25
• Safety Statements: 16

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 3-Azidoanisole

There total 10 articles about 3-Azidoanisole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

m-Anisidine (536-90-3,918666-97-4) → 3-methoxyphenyl azide (3866-16-8)

Guidance literature:

With tert.-butylnitrite; trimethylsilylazide; In acetonitrile; at 0 - 20 ℃; for 1h;

DOI:10.1039/c3cc43838d

Reference yield: 99.0%

3-methoxyphenyl bromide (2398-37-0) → 3-methoxyphenyl azide (3866-16-8)

Guidance literature:

With sodium azide; In ethylene glycol; at 100 ℃; for 3h; Green chemistry;

DOI:10.1039/c8ra04608e

Reference yield: 99.0%

3-methoxy-1-iodobenzene (766-85-8) → 3-methoxyphenyl azide (3866-16-8)

Guidance literature:

With sodium azide; In ethylene glycol; at 100 ℃; for 3h; Green chemistry;

DOI:10.1039/c8ra04608e

upstream raw materials:

m-Anisidine

(3-methoxyphenyl)hydrazine

3-methoxyphenyl bromide

3-methoxyphenylboronic acid

Downstream raw materials:

m-Anisidine

2-[1-(3-methoxyphenyl)-1H-1,2,3-triazol-5-yl]pyridine

5-(4-bromophenyl)-1-(3-methoxyphenyl)-1H-1,2,3-triazole

((2S,6S,8S)-8-(1-(3-methoxyphenyl)-1H-1,2,3-triazol-4-yl)-1,7-dioxaspiro[5.5]undecan-2-yl)methanol

Refernces

• 1、 Akolkar, Satish V.,Khedkar, Vijay M.,Nagargoje, Amol A.,Pisal, Parshuram M.,Sangshetti, Jaiprakash N.,Shingate, Bapurao B.,Siddiqui, Madiha M.. "[HDBU][HSO4]-catalyzed facile synthesis of new 1,2,3-triazole-tethered 2,3-dihydroquinazolin-4[1H]-one derivatives and their DPPH radical scavenging activity". . . Retrieved 2022/01/19.
• 2、 Chiarelli, Laurent R.,Fan, Dongguang,Han, Quanquan,Lu, Yu,Qiao, Chunhua,Shi, Rui,Stelitano, Giovanni,Wang, Bin,Huszár, Stanislav,Miku?ová, Katarína,Savková, Karin. "Structural and Activity Relationships of 6-Sulfonyl-8-Nitrobenzothiazinones as Antitubercular Agents". supporting information. p. 14526 - 14539. Retrieved 2021/10/26.