1,2-Benzenedicarboxylic acid, 4-chloro-, diethyl ester

Base Information

• Chemical Name: 1,2-Benzenedicarboxylic acid, 4-chloro-, diethyl ester
• CAS No.: 38717-95-2
• Molecular Formula: C12H13ClO4
• Molecular Weight: 256.686
• Mol file: 38717-95-2.mol

Synonyms:

Chemical Property of 1,2-Benzenedicarboxylic acid, 4-chloro-, diethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-Benzenedicarboxylic acid, 4-chloro-, diethyl ester

There total 6 articles about 1,2-Benzenedicarboxylic acid, 4-chloro-, diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

ethanol (64-17-5) + monosodique de l'acide chloro-4 phtalique (56047-23-5) → 4-chlorodiethylphthalate (38717-95-2)

Guidance literature:

With hydrogenchloride; at 80 ℃; for 48h;

Reference yield:

→ 4-chlorodiethylphthalate (38717-95-2)

Guidance literature:

With copper(l) chloride;

Reference yield:

monosodique de l'acide chloro-4 phtalique (56047-23-5) → 4-chlorodiethylphthalate (38717-95-2)

Guidance literature:

Multi-step reaction with 3 steps

1: H₂SO₄ / acetic anhydride / 3 h / Heating

2: 2 h / Heating

3: 1.) SOCl₂ / 1.) reflux; 2.) benzene, reflux, 1.5 h

With thionyl chloride; sulfuric acid; In acetic anhydride;

DOI:10.1016/0223-5234(87)90054-7

upstream raw materials:

ethanol

4-chlorophthalic acid

monosodique de l'acide chloro-4 phtalique

Refernces

• 1、 Leblois, Danielle,Piessard, Sylvie,Baut, Guillaume Le,Kumar, Piyush,Brion, Jean-Daniel,et al.. "Pyrophtalones VII. Synthese et activite anti-inflammatoire de (pyridinyl-4)-2 indanediones-1,3 substituees sur le noyau benzenique et/ou sur l'heterocycle". . p. 229 - 238. Retrieved 2007/10/02.