1β-Methyl-4β-isopropyl-1α-cyclohexanol

Base Information

• Chemical Name: 1β-Methyl-4β-isopropyl-1α-cyclohexanol
• CAS No.: 3901-93-7
• Molecular Formula: C10H20O
• Molecular Weight: 156.268
• Mol file: 3901-93-7.mol

Synonyms:1r-Hydroxy-4t-isopropyl-1-methyl-cyclohexan;1-Methyl-4t-isopropyl-cyclohexan-r-ol;4-Isopropyl-1-methyl-cyclohexanol;trans-p-menthan-1-ol;cis-p-menthan-1-ol;hydroxy-1 p-menthane;trans p-menthanol;

Chemical Property of 1β-Methyl-4β-isopropyl-1α-cyclohexanol

Chemical Property:

• Boiling Point: 84 - 85.5 °C (10 mmHg)
• PSA: 20.23000
• LogP: 2.58360

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1β-Methyl-4β-isopropyl-1α-cyclohexanol

There total 36 articles about 1β-Methyl-4β-isopropyl-1α-cyclohexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

trans epoxyde du carvomenthene (3626-19-5,4680-25-5,4959-34-6,5034-17-3,5034-18-4,51424-68-1) → (Z)-4-isopropyl-1-methylcyclohexan-1-ol (3901-93-7) + 5-isopropyl-2-methylcyclohexan-1-ol (499-69-4,1126-39-2,1126-40-5,1126-41-6,1845-59-6,3127-80-8,3858-43-3,3858-45-5,3858-47-7,3858-49-9,5563-78-0,42846-32-2,60320-28-7,116783-34-7)

Guidance literature:

With lithium aluminium tetrahydride;

DOI:10.1016/S0040-4020(01)98846-5

Reference yield: 5.71%

Menthane (99-82-1,1678-82-6,6069-98-3,129939-70-4,129939-71-5) → p-menthan-8-ol (498-81-7) + 1-methyl-4-(1-methylethyl)cyclohexanol (3901-93-7,3901-95-9,21129-27-1) + p-menthane-4-ol (470-65-5)

Guidance literature:

With deuterioporphyrin dimethyl ester ferric chloride; In dichloromethane; at 130 ℃; for 18h; Reagent/catalyst; Temperature; Catalytic behavior;

Reference yield:

Menthane (99-82-1,1678-82-6,6069-98-3,129939-70-4,129939-71-5) → (Z)-p-menthan-4-ol (3239-03-0) + (Z)-4-isopropyl-1-methylcyclohexan-1-ol (3901-93-7) + isomenthone (491-07-6,17627-49-5,7786-64-3) + (+/-)-menthone (491-07-6,1074-95-9,1196-31-2,3391-87-5,10458-14-7,14073-97-3,18309-28-9,36977-92-1,117773-78-1,89-80-5,17627-49-5,7786-64-3)

Guidance literature:

Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given;

DOI:10.1016/S0040-4020(01)96644-X

upstream raw materials:

ascaridole

beta-terpineol

(+)-p-menth-1-ene

dihydro-β-terpinyl acetate

Downstream raw materials:

p-menth-1-ene

Refernces

• 1、 Xu, Shichao,Zhao, Zhendong,Bi, Liangwu,Chen, Yuxiang,Li, Dongmei,Wang, Jing,Gu, Yan,Lu, Yanju. "Selective aerobic hydroxylation of p-menthane to dihydroterpineols catalyzed by metalloporphyrins in solvent and additive free system". . p. 26 - 29. Retrieved 2014/12/11.
• 2、 Atkins, Robert,Carless, Howard A. J.. "PHOTO-OXIDATION OF α-PHELLANDRENE: THE FORMATION OF CYCLOHEXADIENYL HYDROPEROXIDES AND THEIR REDUCTION TO ARENE 1,4-HYDRATES". . p. 6093 - 6096. Retrieved 2007/10/02.