4-Pentenoic acid, 2-acetyl-, 1,1-dimethylethyl ester

Base Information

• Chemical Name: 4-Pentenoic acid, 2-acetyl-, 1,1-dimethylethyl ester
• CAS No.: 39149-69-4
• Molecular Formula: C11H18O3
• Molecular Weight: 198.262
• Mol file: 39149-69-4.mol

Synonyms:

Chemical Property of 4-Pentenoic acid, 2-acetyl-, 1,1-dimethylethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Pentenoic acid, 2-acetyl-, 1,1-dimethylethyl ester

There total 1 articles about 4-Pentenoic acid, 2-acetyl-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

3-benzylimino-butyric acid tert-butyl ester + allyl-trimethyl-silane (762-72-1) → 2-(1-benzyliminoethyl)pent-4-enoic acid tert-butyl ester + tert-butyl 2-acetyl-4-pentenoate (39149-69-4)

Guidance literature:

3-benzylimino-butyric acid tert-butyl ester; allyl-trimethyl-silane; In acetonitrile; at 20 ℃;

With triethylamine; In hexane; ethyl acetate; at 20 ℃; for 0.5h;

DOI:10.1021/jo048955d

Reference yield: 80.0%

tert-butyl 2-acetyl-4-pentenoate (39149-69-4) + dibenzyl azodicarboxylate (2449-05-0) → C27H32N2O7

Guidance literature:

With copper(II) bis(trifluoromethanesulfonate); (S,S)-2,2'-isopropylidenebis(4-phenyl-2-oxazoline); In dichloromethane;

DOI:10.1002/anie.200390350

Reference yield: 49.0%

tert-butyl 2-acetyl-4-pentenoate (39149-69-4) + 1-iodo-3,4-dimethoxybenzene (5460-32-2) → tert-butyl (E)-2-acetyl-5-(3,4-dimethoxyphenyl)pent-4-enoate

Guidance literature:

With palladium diacetate; triethylamine; In acetonitrile; at 85 ℃; for 15h; Inert atmosphere;

DOI:10.1002/anie.201600766

upstream raw materials:

allyl-trimethyl-silane

Downstream raw materials:

2-Allyl-2-tert-butoxycarbonyl-5-hydroxy-5-methyl-cyclohexan-1-on

2-Acetyl-2-((Z)-2-benzenesulfonyl-1-bromomethyl-vinyl)-pent-4-enoic acid tert-butyl ester

6-Allyl-2-cyclohexenone

2-Acetyl-2-(3-oxo-propyl)-pent-4-enoic acid tert-butyl ester

Refernces