(-)-Nopol

Base Information Edit

Chemical Name:(-)-Nopol
CAS No.:35836-73-8
Molecular Formula:C11H18 O
Molecular Weight:166.263
Hs Code.:29061900
European Community (EC) Number:252-744-2
UNII:XK8HU7WJQC,149HVE6X29
DSSTox Substance ID:DTXSID601044956
Nikkaji Number:J319.539B
Wikidata:Q27251609
Mol file:35836-73-8.mol

Synonyms:nopol

Suppliers and Price of (-)-Nopol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(-)-Nopol
25g
$ 185.00

Sigma-Aldrich
(1R)-(?)-Nopol 98%
100ml
$ 52.20

Medical Isotopes, Inc.
(-)-Nopol
100 g
$ 825.00

Crysdot
2-((1R,5S)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethanol 95+%
100g
$ 692.00

American Custom Chemicals Corporation
(-)-NOPOL 95.00%
5G
$ 818.00

American Custom Chemicals Corporation
(-)-NOPOL 95.00%
1G
$ 626.08

Ambeed
2-((1R,5S)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethanol 98+%
500g
$ 148.00

Ambeed
2-((1R,5S)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethanol 98+%
100g
$ 37.00

Ambeed
2-((1R,5S)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethanol 98+%
25g
$ 10.00

AK Scientific
(-)-Nopol
5g
$ 186.00

Total 56 raw suppliers

Chemical Property of (-)-Nopol Edit

Chemical Property:

Vapor Pressure:0.00937mmHg at 25°C
Refractive Index:n20/D 1.493
Boiling Point:235°Cat760mmHg
PKA:15.03±0.10(Predicted)
Flash Point:98.9°C
PSA：20.23000
Density:0.978g/cm³
LogP:2.36120
Storage Temp.:Refrigerator, under inert atmosphere
Solubility.:Chloroform (Slightly), Methanol (Slightly)
Water Solubility.:333.5mg/L at 20℃
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:166.135765193
Heavy Atom Count:12
Complexity:215

Purity/Quality:

95%, 99% ^*data from raw suppliers

(-)-Nopol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22-36/37/38
Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC1(C2CC=C(C1C2)CCO)C
Isomeric SMILES:CC1([C@H]2CC=C([C@@H]1C2)CCO)C
Uses (-)-Nopol, is a chiral building block used in chemical synthesis. It is an intermediate that can be used for the synthesis of bulky moiety-modified analogs to the sandalwood odorant Polysantol.

Technology Process of (-)-Nopol

There total 12 articles about (-)-Nopol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 794586-63-3
(1R,5S)-6,6-dimethyl-2-<2-(tetrahydropyran-2-yloxy)ethyl>bicyclo<3.1.1>hept-2-ene

: 35836-73-8
(1R)-(-)-nopol

Guidance literature:: With trichloroisocyanuric acid; In methanol; at 20 ℃; for 4h;
DOI:10.1081/SCC-200031053

Reference yield: 89.0%

: 2-(2-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 35836-73-8
(1R)-(-)-nopol

Guidance literature:: 2-(2-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; With sodium perborate tetrahydrate; water; In tetrahydrofuran; at 40 ℃; for 0.0166667h; Schlenk technique; Flow reactor;

With sodium thiosulfate; In tetrahydrofuran; Schlenk technique; Flow reactor;
DOI:10.1021/acs.orglett.1c01222