Technology Process of 6-amino-1,2-dihydro-4H-[1,2,3]triazolo[4,5-c]pyridin-4-one
There total 7 articles about 6-amino-1,2-dihydro-4H-[1,2,3]triazolo[4,5-c]pyridin-4-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
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Multi-step reaction with 7 steps
1: 88.9 percent / conc. sulfuric acid / H2O; methanol / 2 h
2: 90 percent / p-toluenesulfonyl azide, 1,5-diazabicyclo<5.4.0>undec-5-ene / ethyl acetate / 1 h / Ambient temperature
3: 82.3 percent / hydrogen / platinum oxide / acetic acid; 2-methoxy-ethanol / 4 h / 1810.02 Torr / Ambient temperature
4: 54.3 percent / conc. ammonium hydroxide / 8 h / Ambient temperature
5: 78.3 percent / phosphoryl chloride / 1.5 h / Heating
6: 81.4 percent / liquid ammonia / 10 h / 100 - 110 °C / in a steel bomb
7: 59.5 percent / 10percent sodium carbonate / H2O / 1 h / Heating
With
ammonium hydroxide; 4-toluenesulfonyl azide; sulfuric acid; ammonia; hydrogen; sodium carbonate; 1,5-Diazabicyclo[5.4.0]undec-5-ene; trichlorophosphate;
platinum(IV) oxide;
In
methanol; 2-methoxy-ethanol; water; acetic acid; ethyl acetate;
DOI:10.1002/jhet.5570170132
