Oxaziridine, 2-methyl-3-phenyl-, (2R,3S)-rel-

Base Information

• Chemical Name: Oxaziridine, 2-methyl-3-phenyl-, (2R,3S)-rel-
• CAS No.: 39245-63-1
• Molecular Formula: C8H9NO
• Molecular Weight: 135.166
• Mol file: 39245-63-1.mol

Synonyms:

Chemical Property of Oxaziridine, 2-methyl-3-phenyl-, (2R,3S)-rel-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Oxaziridine, 2-methyl-3-phenyl-, (2R,3S)-rel-

There total 8 articles about Oxaziridine, 2-methyl-3-phenyl-, (2R,3S)-rel- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

N-Benzylidenemethylamine (622-29-7) → 2-methyl-3-phenyl-oxaziridine (3400-12-2,39245-63-1,40264-03-7,67462-99-1,67463-00-7,182824-63-1)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In methanol; at 0 ℃; for 0.5h;

DOI:10.1016/S0040-4020(01)89569-7

Reference yield:

N-Benzylidenemethylamine (622-29-7) → trans-2-methyl-3-phenyloxaziridine (40264-03-7) + cis-2-methyl-3-phenyloxaziridine (39245-63-1) + benzaldehyde (100-52-7)

Guidance literature:

With tetrabutylammonium Oxone; In acetonitrile; at 20 ℃; for 0.583333h; Further Variations:; Solvents; Reagents; Product distribution;

DOI:10.1016/j.tetlet.2003.10.107

Reference yield:

N-methyl-α-phenylnitrone (3376-23-6) → 2-methyl-3-phenyl-oxaziridine (3400-12-2,39245-63-1,40264-03-7,67462-99-1,67463-00-7,182824-63-1)

Guidance literature:

In [⁽²⁾H₆]acetone; at 20 ℃; for 72h; Inert atmosphere; UV-irradiation;

DOI:10.1039/c5ob01277e

upstream raw materials:

N-Benzylidenemethylamine

benzylidenamine

N-(9H-fluoren-9-ylidene)-1-phenylmethanamine

C₂₀H₁₅NO

Downstream raw materials:

C-phenyl-N-methylnitrone

[(S)-2-((R)-Benzenesulfinyl)-1-phenyl-ethyl]-methyl-amine

N-allyl-N-methylbenzamide

ethene

Refernces

• 1、 Itoh, Kennosuke,Kato, Ryo,Kinugawa, Daito,Kamiya, Hideaki,Kudo, Ryuki,Hasegawa, Masayuki,Fujii, Hideaki,Suga, Hiroyuki. "Photochemically-induced C-C bond formation between tertiary amines and nitrones". supporting information. p. 8919 - 8924. Retrieved 2015/08/24.
• 2、 Singhal, Sweety,Jain, Suman L.,Prasad,Sain, Bir. "An environmentally friendly oxidation system for the selective oxygenation of aldimines to oxaziridines with anhydrous TBHP and alumina-supported MoO 3 as a recyclable heterogeneous catalyst". . p. 2051 - 2054. Retrieved 2008/02/04.