DL 3-117

Base Information

• Chemical Name: DL 3-117
• CAS No.: 80450-47-1
• Molecular Formula: C₃₇H₄₈I₆N₆O₁₈
• Molecular Weight: 1626.24
• Mol file: 80450-47-1.mol

Synonyms:

Chemical Property of DL 3-117

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of DL 3-117

There total 3 articles about DL 3-117 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.6%

5,5'-(N,N-dimethylmalonyldiimino)-bis(N1,N3-bis(6-hydroxy-2,2-dimethyldioxepan-5-imino))-2,4,6-triiodoisophthalamide → IOTROLAN (79770-24-4,80450-47-1)

Guidance literature:

With hydrogenchloride; In water; at 20 ℃; for 24h; Concentration;

Reference yield:

2,4,6-triiodo-5-(methylamino)isophthalic acid (40976-89-4) → IOTROLAN (79770-24-4,80450-47-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: Aliquat 336; thionyl chloride / toluene / 8 h / 70 - 90 °C

1.2: 6 h / 75 - 80 °C / Inert atmosphere

2.1: triethylamine / N,N-dimethyl acetamide / 20 h / 20 °C / Cooling with ice

3.1: hydrogenchloride / water / 24 h / 20 °C

With hydrogenchloride; thionyl chloride; Aliquat 336; triethylamine; In N,N-dimethyl acetamide; water; toluene;

Reference yield:

2,4,6-triiodo-5-aminoisophthalic acid (35453-19-1) → IOTROLAN (79770-24-4,80450-47-1)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sulfuric acid / methanol / 3 h / 45 - 50 °C

2.1: Aliquat 336; thionyl chloride / toluene / 8 h / 70 - 90 °C

2.2: 6 h / 75 - 80 °C / Inert atmosphere

3.1: triethylamine / N,N-dimethyl acetamide / 20 h / 20 °C / Cooling with ice

4.1: hydrogenchloride / water / 24 h / 20 °C

With hydrogenchloride; thionyl chloride; sulfuric acid; Aliquat 336; triethylamine; In methanol; N,N-dimethyl acetamide; water; toluene;

upstream raw materials:

2,4,6-triiodo-5-(methylamino)isophthalic acid

2,4,6-triiodo-5-aminoisophthalic acid

Refernces