1-ethyl-2-[(1E,3Z)-3-(1-ethylquinolin-2(1H)-ylidene)prop-1-en-1-yl]quinolinium

Base Information

• Chemical Name: 1-ethyl-2-[(1E,3Z)-3-(1-ethylquinolin-2(1H)-ylidene)prop-1-en-1-yl]quinolinium
• CAS No.: 15185-48-5
• Molecular Formula: C₂₅H₂₅N₂*I
• Molecular Weight: 480.391
• Mol file: 15185-48-5.mol

Synonyms:Trimethinecyanineiodide, [2-bis(1-ethylquinolyl)]-

Chemical Property of 1-ethyl-2-[(1E,3Z)-3-(1-ethylquinolin-2(1H)-ylidene)prop-1-en-1-yl]quinolinium

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-ethyl-2-[(1E,3Z)-3-(1-ethylquinolin-2(1H)-ylidene)prop-1-en-1-yl]quinolinium

There total 16 articles about 1-ethyl-2-[(1E,3Z)-3-(1-ethylquinolin-2(1H)-ylidene)prop-1-en-1-yl]quinolinium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-ethyl-2-methylquinolinium iodide (606-55-3) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 1,1'-diethyl-2,2'-quinocarbocyanine iodide (605-91-4,15185-48-5)

Guidance literature:

With triethylamine; trichlorophosphate; Heating;

Reference yield:

1-ethyl-2-methylquinolinium iodide (606-55-3) + N-ethyl-2-methylbenzothiazolium iodide (3119-93-5) + (E)-N,N'-bis(4-methoxyphenyl)formimidamide (141417-87-0,1152-75-6) → pinacyanol iodide (605-91-4,15185-48-5) + 1-ethyl-2-[3-(3-ethyl-3H-benzothiazol-2-ylidene)-propenyl]-quinolinium; iodide

Guidance literature:

1-ethyl-2-methylquinolinium iodide; (E)-N,N'-bis(4-methoxyphenyl)formimidamide; With orthoformic acid triethyl ester; In ethanol; Heating;

With sulfonyl chloride resin; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃;

N-ethyl-2-methylbenzothiazolium iodide; With pyridine; N-ethyl-N,N-diisopropylamine; at 20 ℃; Further stages.;

DOI:10.1021/ol026836j

Reference yield:

1-ethyl-2-methylquinolinium iodide (606-55-3) + N-ethyl-4-methylquinolinium iodide (605-59-4) + (E)-N,N'-bis(4-methoxyphenyl)formimidamide (141417-87-0,1152-75-6) → pinacyanol iodide (605-91-4,15185-48-5) + 1-ethyl-2-[3-(1-ethyl-1H-quinolin-4-ylidene)-propenyl]-quinolinium; iodide

Guidance literature:

1-ethyl-2-methylquinolinium iodide; (E)-N,N'-bis(4-methoxyphenyl)formimidamide; With orthoformic acid triethyl ester; In ethanol; Heating;

With sulfonyl chloride resin; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃;

N-ethyl-4-methylquinolinium iodide; With pyridine; N-ethyl-N,N-diisopropylamine; at 20 ℃; Further stages.;

DOI:10.1021/ol026836j

upstream raw materials:

formaldehyd

1-ethyl-2-methylquinolinium iodide

orthoformic acid triethyl ester

Glyoxilic acid

Downstream raw materials:

Toluene-4-sulfonate1-ethyl-2-{(E)-3-[1-ethyl-1H-quinolin-(2E)-ylidene]-propenyl}-quinolinium;

Refernces

• 1、 Mason, Stephen J.,Balasubramanian, Shankar. "Solid-phase catch, activate, and release synthesis of cyanine dyes". . p. 4261 - 4264. Retrieved 2002.
• 2、 Makin, S. M.,Pomogaev, A. I.. "CONDENSATION OF VILSMEIER COMPLEXES WITH HETEROCYCLIC COMPOUNDS. SYNTHESIS OF CARBOCYANINES". . p. 1916 - 1918. Retrieved 2007/10/02.