Furan, 4-methyl-2-phenyl-

Base Information

• Chemical Name: Furan, 4-methyl-2-phenyl-
• CAS No.: 39517-83-4
• Molecular Formula: C11H10O
• Molecular Weight: 158.2
• Mol file: 39517-83-4.mol

Synonyms:

Chemical Property of Furan, 4-methyl-2-phenyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Furan, 4-methyl-2-phenyl-

There total 33 articles about Furan, 4-methyl-2-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-Phenyl-4-<(phenylsulfonyl)methyl>furan (128496-99-1) → 4-methyl-2-phenylfuran (39517-83-4)

Guidance literature:

With sodium dihydrogenphosphate; sodium amalgam; In methanol; Ambient temperature;

DOI:10.1021/jo00030a025

Reference yield: 98.0%

2-methylene-4-phenylbut-3-yn-1-ol (57951-69-6) → 4-methyl-2-phenylfuran (39517-83-4)

Guidance literature:

With silver hexafluoroantimonate; (tBuNH)(Et₂N)CAuNTf₂; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1002/ejoc.201001479

Reference yield: 90.0%

2-Methylenecyclopropyl Phenyl Ketone (130012-70-3) → 4-methyl-2-phenylfuran (39517-83-4)

Guidance literature:

With sodium iodide; In acetone; for 42h; Heating;

DOI:10.1021/ja0494860

upstream raw materials:

2-methyl-4-methylene-2-phenyl-[1,3]dioxolane

2-Phenyl-4-<(phenylsulfonyl)methyl>furan

3-[(2-bromo-1-methoxy-1-phenyl)-ethoxy]-propyne

3-Hydroxy-3-methyl-1-phenyl-4-(tetrahydro-pyran-2-yloxy)-butan-1-one

Downstream raw materials:

(+/-)(1Ξ,2Ξ)-5-methyl-1-phenyl-7-oxa-norborn-5-ene-2r,3c-dicarboxylic acid-anhydride

Refernces

• 1、 Lee, Robert J.,Lindley, Martin R.,Pritchard, Gareth J.,Kimber, Marc C.. "A biosynthetically inspired route to substituted furans using the Appel reaction: Total synthesis of the furan fatty acid F5". supporting information. p. 6327 - 6330. Retrieved 2017/07/11.
• 2、 Pauli, Larissa,Tannert, Re,Scheil, Robin,Pfaltz, Andreas. "Asymmetric hydrogenation of furans and benzofurans with iridium-pyridine-phosphinite catalysts". . p. 1482 - 1487. Retrieved 2015/01/30.