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7-Hydroxyphthalide

Base Information Edit
  • Chemical Name:7-Hydroxyphthalide
  • CAS No.:3956-91-0
  • Molecular Formula:C8H6O3
  • Molecular Weight:150.134
  • Hs Code.:
  • DSSTox Substance ID:DTXSID20473979
  • Metabolomics Workbench ID:118577
  • Nikkaji Number:J1.514.648F
  • Wikidata:Q75057987
  • Mol file:3956-91-0.mol
7-Hydroxyphthalide

Synonyms:7-hydroxy-3H-isobenzofuran-1-one;7-hydroxyphthalide

Suppliers and Price of 7-Hydroxyphthalide
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
Total 3 raw suppliers
Chemical Property of 7-Hydroxyphthalide Edit
Chemical Property:
  • XLogP3:1.5
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:0
  • Exact Mass:150.031694049
  • Heavy Atom Count:11
  • Complexity:178
Purity/Quality:

95% *data from raw suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:C1C2=C(C(=CC=C2)O)C(=O)O1
Technology Process of 7-Hydroxyphthalide

There total 1 articles about 7-Hydroxyphthalide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With sodium tetrahydroborate; In N,N-dimethyl-formamide; at 20 ℃; for 2h;
DOI:10.1271/bbb.65.990
Guidance literature:
With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;
DOI:10.1021/ol200498k
Guidance literature:
Multi-step reaction with 3 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 20 °C / Inert atmosphere
2.1: diisobutylaluminium hydride / hexanes; dichloromethane / 3.5 h / -78 °C / Inert atmosphere
2.2: 0.5 h / -40 - 20 °C / Inert atmosphere
3.1: toluene-4-sulfonic acid / 2 h / 20 °C / Molecular sieve; Inert atmosphere
With diisobutylaluminium hydride; potassium carbonate; toluene-4-sulfonic acid; In hexanes; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ol200498k
Refernces Edit
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