6-Iodo-1-Hexanol

Base Information

• Chemical Name: 6-Iodo-1-Hexanol
• CAS No.: 40145-10-6
• Molecular Formula: C6H13IO
• Molecular Weight: 228.073
• Mol file: 40145-10-6.mol

Synonyms:

Chemical Property of 6-Iodo-1-Hexanol

Chemical Property:

• PSA: 20.23000
• LogP: 1.97410

Purity/Quality:

99%, ^*data from raw suppliers

6-Iodohexan-1-ol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-Iodo-1-Hexanol

There total 7 articles about 6-Iodo-1-Hexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

6-chloro-1-hexanol (2009-83-8) → 1-iodohexan-6-ol (40145-10-6)

Guidance literature:

With sodium iodide; In acetone; Reflux;

DOI:10.1021/acs.orglett.9b01951

Reference yield: 93.0%

1,6-hexanediol (629-11-8) → 1-iodohexan-6-ol (40145-10-6)

Guidance literature:

With iodine; In acetonitrile; at 120 ℃; for 0.05h; chemoselective reaction; Microwave irradiation;

DOI:10.17344/acsi.2015.1478

Reference yield: 91.0%

1-bromo-6-hexanol (4286-55-9) → 1-iodohexan-6-ol (40145-10-6)

Guidance literature:

With sodium iodide; In acetone; for 15h; Reflux;

DOI:10.1021/acs.joc.1c00383

upstream raw materials:

1,6-hexanediol

6-chloro-1-hexanol

1-bromo-6-hexanol

ethyl 6-iodohexanoate

Downstream raw materials:

6-hydroxyhexyl-triphenylphosphonium iodide

2-Allyl-2-(6-hydroxy-hexyl)-cyclohexane-1,3-dione

oct-7-en-1-ol

oct-7-en-1-yl 4-methylbenzenesulfonate

Refernces

• 1、 Cheng, Jun,Saghi-Szabo, Gotthard,Tossell, John A.,Miller, Cary J.. "Modulation of Electronic Coupling through Self-Assembled Monolayers via Internal Chemical Modification". . p. 680 - 684. Retrieved 1996.
• 2、 Chen, Yifeng,Huang, Wenyi,Qu, Jingping,Shrestha, Mohini,Wang, Yun,Weng, Yangyang. "Nickel-Catalyzed Formal Aminocarbonylation of Unactivated Alkyl Iodides with Isocyanides". supporting information. p. 3245 - 3250. Retrieved 2020/04/21.
• 3、 Karabiyikoglu, Sedef,Boon, Byron A.,Merlic, Craig A.. "Cycloaddition Reactions of Cobalt-Complexed Macrocyclic Alkynes: The Transannular Pauson-Khand Reaction". . p. 7732 - 7744. Retrieved 2017/08/14.