4-Thiazoleacetamide

Base Information

• Chemical Name: 4-Thiazoleacetamide
• CAS No.: 51551-54-3
• Molecular Formula: C5H6N2OS
• Molecular Weight: 142.18
• Hs Code.: 2934100090
• Mol file: 51551-54-3.mol

Synonyms:4-Thiazoleacetamide;

Chemical Property of 4-Thiazoleacetamide

Chemical Property:

• Vapor Pressure: 6.63E-06mmHg at 25°C
• Refractive Index: 1.593
• Boiling Point: 377.7 °C at 760 mmHg
• Flash Point: 182.2 °C
• PSA: 84.22000
• Density: 1.344 g/cm³
• LogP: 0.87120

Purity/Quality:

98%min ^*data from raw suppliers

2-(1,3-thiazol-4-yl)acetamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Thiazoleacetamide

There total 1 articles about 4-Thiazoleacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

thiazol-4-yl acetic acid ethyl ester (120155-43-3) → -acetamid (51551-54-3)

Guidance literature:

With ammonium hydroxide;

DOI:10.1021/jo01166a021 DOI:10.1039/jr9460000091

Reference yield:

-acetamid (51551-54-3) → 2-(thiazol-4-yl)acetonitrile (7709-59-3)

Guidance literature:

With phosphorus pentoxide; unter vermindertem Druck;

Reference yield:

-acetamid (51551-54-3) → 4-TEA (7728-74-7)

Guidance literature:

Multi-step reaction with 2 steps

1: P₂O₅ / unter vermindertem Druck

2: Raney nickel; NH₃; ethanol / Hydrogenation

With ethanol; ammonia; phosphorus pentoxide; nickel;

upstream raw materials:

thiazol-4-yl acetic acid ethyl ester

Downstream raw materials:

2-(thiazol-4-yl)acetonitrile

4-TEA