2-Naphthyl p-Toluenesulfonate

Base Information

• Chemical Name: 2-Naphthyl p-Toluenesulfonate
• CAS No.: 7385-85-5
• Molecular Formula: C17H14O3S
• Molecular Weight: 298.362
• Mol file: 7385-85-5.mol

Synonyms:naphthalen-2-yl 4-methylbenzenesulfonate;

Chemical Property of 2-Naphthyl p-Toluenesulfonate

Chemical Property:

• Vapor Pressure: 8.61E-09mmHg at 25°C
• Melting Point: 123.0 to 127.0 °C
• Boiling Point: 476.7°C at 760 mmHg
• Flash Point: 242.1°C
• PSA: 51.75000
• Density: 1.277g/cm³
• LogP: 4.99670

Purity/Quality:

98% ^*data from raw suppliers

2-Naphthyl p-Toluenesulfonate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Naphthyl p-Toluenesulfonate

There total 13 articles about 2-Naphthyl p-Toluenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

p-toluenesulfonyl chloride (98-59-9) + β-naphthol (135-19-3) → naphthalen-2-yl tosylate (7385-85-5)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; water; at 0 - 20 ℃; for 2h; Green chemistry;

DOI:10.1055/s-0034-1378867

Reference yield: 97.0%

N,N-dimethyl-1-(p-tolylsulfonyl)pyridin-1-ium-4-amine chloride (72973-25-2) + β-naphthol (135-19-3) → naphthalen-2-yl tosylate (7385-85-5)

Guidance literature:

In dichloromethane; at 20 ℃; for 0.0333333h; Solvent; Green chemistry;

DOI:10.1016/j.tetlet.2016.09.010

Reference yield: 88.0%

p-toluenesulfonylanhydride (4124-41-8) + β-naphthol (135-19-3) → naphthalen-2-yl tosylate (7385-85-5)

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; In dichloromethane; at 0 - 20 ℃; Inert atmosphere; Glovebox; Schlenk technique;

DOI:10.1039/c6cc09685a

upstream raw materials:

toluene-4-sulfonic acid

β-naphthol

p-toluenesulfonyl chloride

sodium 4-methylbenzenesulfinate

Downstream raw materials:

1-tosylnaphthalen-2-ol

2-phenylnaphthalene

naphthalene

2-(2-methylphenyl)naphthalene

Refernces

• 1、 Khan, Ajmir,Silva, Luiz F.,Rabnawaz, Muhammad. "A comparative study of thallium(iii) and iodine(iii)-mediated ring contraction reactions for the synthesis of indane". . p. 2078 - 2084. Retrieved 2021/02/06.
• 2、 Roger, Julien,Hierso, Jean-Cyrille. "Phenol Derivatives in Ruthenium-Catalyzed C–H Arylation: A General Synthetic Access to Azole-Based Congested Polyaromatics". supporting information. p. 4953 - 4958. Retrieved 2018/09/25.