3-Hydroxybenzoyl chloride

Base Information Edit

Chemical Name:3-Hydroxybenzoyl chloride
CAS No.:40812-76-8
Molecular Formula:C7H5ClO2
Molecular Weight:156.569
Hs Code.:2914790090
DSSTox Substance ID:DTXSID60513520
Nikkaji Number:J1.220.384E
Wikidata:Q82373376
Mol file:40812-76-8.mol

Synonyms:3-hydroxybenzoyl chloride;40812-76-8;Benzoyl chloride, 3-hydroxy- (9CI);SCHEMBL1456040;DTXSID60513520;AKOS009218137;FT-0774534

Suppliers and Price of 3-Hydroxybenzoyl chloride

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-HydroxybenzoylChloride
1g
$ 255.00

Matrix Scientific
3-Hydroxybenzoylchloride
1g
$ 594.00

Atlantic Research Chemicals
3-Hydroxybenzoylchloride 95%
1gm:
$ 279.23

Total 3 raw suppliers

Chemical Property of 3-Hydroxybenzoyl chloride Edit

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:155.9978071
Heavy Atom Count:10
Complexity:136

Purity/Quality:

99%min. ^*data from raw suppliers

3-HydroxybenzoylChloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)O)C(=O)Cl
Uses 3-Hydroxybenzoyl Chloride is a useful reagent in preparation and the biological activities of substituted 1,3,4-oxadiazole derivatives.

Technology Process of 3-Hydroxybenzoyl chloride

There total 6 articles about 3-Hydroxybenzoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 99-06-9
3-Carboxyphenol

: 40812-76-8
3-hydroxybenzoyl chloride

Guidance literature:: With thionyl chloride; In N,N-dimethyl-formamide; toluene; at 110 ℃;

Reference yield:

: 100-83-4
meta-hydroxybenzaldehyde

: 40812-76-8
3-hydroxybenzoyl chloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium carbonate / 4 h / Reflux

2.1: sodium dihydrogenphosphate; dihydrogen peroxide; sodium chlorite / water; acetonitrile / 1.5 h / 10 - 20 °C

2.2: 0.08 h

3.1: thionyl chloride / dichloromethane; N,N-dimethyl-formamide / 1 h / 20 °C

With sodium chlorite; sodium dihydrogenphosphate; thionyl chloride; dihydrogen peroxide; potassium carbonate; In dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/j.biochi.2012.12.005

Reference yield:

: 1700-37-4
3-Benzyloxybenzaldehyde

: 40812-76-8
3-hydroxybenzoyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium dihydrogenphosphate; dihydrogen peroxide; sodium chlorite / water; acetonitrile / 1.5 h / 10 - 20 °C

1.2: 0.08 h

2.1: thionyl chloride / dichloromethane; N,N-dimethyl-formamide / 1 h / 20 °C

With sodium chlorite; sodium dihydrogenphosphate; thionyl chloride; dihydrogen peroxide; In dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/j.biochi.2012.12.005