3,6-dimethoxyphthalonitrile

Base Information

• Chemical Name: 3,6-dimethoxyphthalonitrile
• CAS No.: 40904-87-8
• Molecular Formula: C10H8N2O2
• Molecular Weight: 188.18300
• Mol file: 40904-87-8.mol

Synonyms:3,6-dimethoxybenzene-1,2-dinitrile;3,6-Dimethoxy-phthalonitril;3,6-dimethoxy-phthalonitrile;3.6-Dimethoxy-phthalsaeure-dinitril;1,4-di(methoxyl)phthalonitrile;1,4-dimethoxy-2,3-dicyanobenzene;

Chemical Property of 3,6-dimethoxyphthalonitrile

Chemical Property:

• PSA: 66.04000
• LogP: 1.44716

Purity/Quality:

99% ^*data from raw suppliers

3,6-Dimethoxyphthalonitrile 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,6-dimethoxyphthalonitrile

There total 6 articles about 3,6-dimethoxyphthalonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2,3-dicyano-1,4-hydroquinone (4733-50-0) + dimethyl sulfate (77-78-1) → 1,4-dimethoxy-2,3-dicyanobenzene (40904-87-8)

Guidance literature:

In butanone; for 18h; Heating;

DOI:10.1021/jm00171a048

Reference yield:

2,3-dicyano-1,4-hydroquinone (4733-50-0) → 1,4-dimethoxy-2,3-dicyanobenzene (40904-87-8)

Guidance literature:

With potassium carbonate; dimethyl sulfate; In water; butanone;

Reference yield:

dimethyl sulfate (77-78-1) → 1,4-dimethoxy-2,3-dicyanobenzene (40904-87-8)

Guidance literature:

With xylene;

DOI:10.1021/ja01224a025

upstream raw materials:

2,3-dicyano-1,4-hydroquinone

dimethyl sulfate

methyl iodide

Methyl methanesulfonate

Downstream raw materials:

3,6-dimethoxyphthalic acid

4,7-dimethoxy-2-phenyl-indan-1,3-dione

3-[(Ξ)-benzylidene-4,7-dimethoxy-phthalide

3,6-dimethoxyphthalic anhydride

Refernces

• 1、 -. "Low hue photobleaches". . . Retrieved 2008/06/13.
• 2、 Krapcho, Paul A.,Petry, Mary E.,Hacker, Miles P.. "Heterosubstituted Anthracene-9,10-dione Analogues. The Synthesis and Antitumor Evaluation of 5,8-Bisnaphthothiophene-4,9-diones". . p. 2651 - 2655. Retrieved 2007/10/02.